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Inducing Hypothermia in Neonatal/Pediatric ECMO Cases

University of Pittsburgh Senior Design - BioE1160 December 5, 2003. Inducing Hypothermia in Neonatal/Pediatric ECMO Cases. Adam Abdulally Erin Aghamehdi Kim Albrecht Rebecca Hrutkay. Overview. There is no means of rapidly cooling pediatric and neonatal ECMO patients.

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Inducing Hypothermia in Neonatal/Pediatric ECMO Cases

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  1. University of Pittsburgh Senior Design - BioE1160 December 5, 2003 Inducing Hypothermia in Neonatal/Pediatric ECMO Cases Adam Abdulally Erin Aghamehdi Kim Albrecht Rebecca Hrutkay

  2. Overview • There is no means of rapidly cooling pediatric and neonatal ECMO patients. • Cooling offers a way to provide neurological protection for the patient. • Solution: A cooling unit that will work in conjunction with pediatric and neonatal ECMO circuits • Current Design Possibilities: • Cooling block • Cooling sleeve

  3. Next Semester Project Goals • High-level timing goals: • January – choose design and start modeling • February – complete computer modeling & analysis • March – research means of building cooling unit

  4. Features & Benefits • Features: • Accurate and rapid cooling • Prevention of neurological damage and patient safety • Patient temperature sensors • Ensure proper cooling • Benefits: • Inducing hypothermia when desirable • Integration into ECMO circuit • Limits amount of new equipment and pick and choose when to use it

  5. Cooling Sleeve

  6. Function Means Tree

  7. Alternative Design

  8. Competitive Analysis • Competitors: • Internal cooling • Non-invasive surface cooling • Strengths: • Simple integration • No additional infused liquids • Weaknesses: • Requires constant monitoring • Limited patient range

  9. Technology • New technology: • Novel reworking of current ideas • Engineering Models: • Solidworks • ANSYS

  10. Team/Resources • Resources allocated: • ECMO circuit • Children’s Hospital • Possible engineering mentor

  11. Schedule & Milestones

  12. Who is going to do what • Everyone – research, modeling, testing • Kim and Rebecca – controller • Adam – heat transfer • Erin – cooling mechanisms

  13. Current Status • Milestones: • Met w/ advisor (Dr. Carcillo) • Completed homework • Two preliminary designs • Talked to perfusionists about the project • Dr. Kameneva about biorheology and heat transfer • Exploring thermal analysis in Ansys

  14. Acknowledgements • Sources of funding • Dr. Carcillo • Mark • Mike Schaffer – perfusionist at Children’s Hospital • Children’s ICU • Dr. Kameneva

  15. Questions?

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