Radiopharmaceutical Production. FDG Synthesizers. STOP. Introduction.
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This module provides basic information on FDG production chemistry. These links will lead you to presentations about the synthesis of FDG in general, how the commercial synthesizers work and some common problems with FDG synthesis. The next slide gives an overview of the commercially available synthesizers.
This module provides an overview of the commercially available FDG synthesis units.
In all cases, please follow the links to the company website to get the latest information on each synthesizer
WEB PAGE ACSI
The Advanced FDG Carousel Dual Synthesis module is a fully automated, single-purpose device that produces sterile, pyrogen-free Fluoro-Deoxy-Glucose (FDG) suitable for human use. The only user intervention required is loading of the starting kits, and removal of the final product. A Lookout based user interface keeps the user informed of the status of the production.
The sequence and length of each process step can be changed easily by editing an Excel spreadsheet.
Lower run costs compared to other systems
True "infinite run" capability on a single box
Extremely small size - two units will fit into a single mini hotcell
Based on Bioscan’s years of experience in demanding commercial FDG labsBioscan FDG-Plus Synthesizer
WEB PAGE BIOSCAN
WEB PAGE GE HEALTHCARE
Synthesizer Fact sheet
Synthesizer Fact sheet
FASTlab™, a automated PET radiochemistry synthesis platform for FDG. FASTlab offers the versatility and flexibility to develop and produce additional fluoride-based tracers
TRACERlab™ offers a complete series of synthesizers for small to medium scale production of PET tracers, addressing both clinical and research needs.
WEB PAGE IBA Molecular
Integrated Fluidic Processor (IFP™) is an innovative solutionfor the automation of a multitude of predefined syntheseswhile offering the benefit of a disposable system.
Synthera® is designed to accommodate a wide range of radiochemistries. Modules can be interconnected in series to implement complex processes. Creation of different tracers only requires changing the IFP™ model. Syntheses are reproduceable.
WEB PAGE KIRAMS
215-4, Gomgneung-Dong, Nowon-Gu, Seoul, 139-706, KoreaTel : 82-2-970-1331 Fax : 82-2-970-1332
WEB PAGE Raytest
fully visible process
ultra fast reactor heating / cooling
magnetic stirrer mixing system
tube lifting system
cartridge product purification
built-in vacuum pump
built-in pressure control
on-line process control
interactive process diagram
fully automatic operation
reported manual intervention
online/offline process development interface
GLP / GMP / 21CFR part 11 compliant
highest yield ( >55%)
acid or base hydrolysis possible
WEB PAGE SIEMENS
Typical System Performance
Yield of synthesis (decay corrected to EOB) > 65%
Set-up time < 20 minutes
Synthesis time ≤ 45 minutes
Clean up time < 35 minutes
Width 24 in (61 cm)
Depth 14 in (36 cm)
Height 19 in (48 cm)
Weight 150 lbs (68 kg)
Explora is registered trademark of Siemens Medical Solutions USA, Inc.
See a Powerpoint presentation about the Siemens Synthesizers
WEB PAGE SUMITOMO
Our 18FDG system is systematized from synthesis module and official approval quality-inspection module and administration dosage module in the lead cover,for radiation exposure reduction