UW
Download
1 / 29

UW APL & CIE Invention to Start Up Jack Gallagher Pierre Mourad - PowerPoint PPT Presentation


  • 98 Views
  • Uploaded on

UW APL & CIE Invention to Start Up Jack Gallagher Pierre Mourad. Agenda. How We Got Started University Resources Intellectual Property Building a Team Business Plan Funding Sources Research Process & Evolution Research Concept Findings Questions. How We Got Started.

loader
I am the owner, or an agent authorized to act on behalf of the owner, of the copyrighted work described.
capcha
Download Presentation

PowerPoint Slideshow about 'UW APL & CIE Invention to Start Up Jack Gallagher Pierre Mourad' - eben


An Image/Link below is provided (as is) to download presentation

Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.


- - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - -
Presentation Transcript
Uw apl cie invention to start up jack gallagher pierre mourad

UW

APL & CIE

Invention to Start Up

Jack Gallagher

Pierre Mourad


Agenda
Agenda

  • How We Got Started

  • University Resources

  • Intellectual Property

  • Building a Team

  • Business Plan

  • Funding Sources

  • Research Process & Evolution

  • Research Concept Findings

  • Questions


How we got started
How We Got Started

  • Random meeting with Allez PhysiOnix

  • Started research at UW in August 2003 (WTC Grants)

  • Negotiated exclusive license to UW technology (Tech Transfer)

  • First patent published in 2005 (Tech Transfer)

  • Funding from founders, private investors (Angels & Venture Capital), WTC research grants, NIH Phase 1 and 2 SBIR grants


University resources
University Resources

  • Applied Physics Laboratory

  • Department of Neurological Surgery

  • Schools of Dentistry and of Public Health

  • Office of Technology Transfer

  • Washington Technology Center (WTC)

  • Washington Research Foundation (WRF Capital)


Intellectual property
Intellectual Property

  • Get a good patent attorney

  • Extensive review of 500 patents before started

  • Patent filed November 2003 (published May 05)

  • Additional patents filed in 2006


Building a team
Building a Team

  • Start with Technical Types

    • Build & prove out technology

  • Need 1 Business / Marketing Type

    • Build vision of future, negotiations, legal work, fund raising

  • Start part time; eventually convert to full time


Business plan
Business Plan

  • How big is the market

  • What is your reason for being i.e. competitive advantage

  • What is your anticipated market share

  • Projected pricing

  • Estimated spending by year

  • Planned exit (Sale, IPO)

  • Capital requirements by year

  • Fund raising strategy


Funding sources
Funding Sources

  • Need a strategy

  • Founders

  • Washington Technology Center (WTC)

  • National Institutes of Health (NIH)

  • Angels

  • Venture Capital



Evolution of research

Internal Testing:

what are the primary benefits?

Concept Testing:

does the concept deliver a benefit?

Evolution of Research

2004-2006

2006-2007

2005-2006

2003-2004

External Testing:

independent confirmation of safety & effectiveness

Optimize Parameters:

what is the optimal technology design?

Univ. of Wash.

& Ultreo

NIH SBIR Phase I Grant

Ultreo, Inc. & Universities

NIH SBIR Phase II Grant

University of Washington

WTC Grants

Ultreo, Inc.

NIH SBIR Phase II Grant



Some details of the research
some details of the research

  • What is old, and how and what old does

  • What is new, and how and what new does

  • More of what new does

  • Summary statement of some partnering lessons I’ve learned


Manual brushes
manual brushes

  • manual brushes move several times per second and clean only at the point of bristle contact


Power brushes
power brushes

  • power brushes move their bristles several hundred times per second and clean primarily at the point of bristle contact, in a manner vastly more efficient than manual brushes.


Power brushes1
power brushes

  • However, even the best power brushes still leave behind significant amounts of plaque in your mouth, much of it in areas where the bristles don’t contact.

www.studentbmj.com/issues/00/10/education/369.php




What is special about the ultreo
what is special about the Ultreo

  • we’ve added optimally configured and delivered ultrasound to a power toothbrush foundation.


What is special about the ultreo1
what is special about the Ultreo

  • the Ultreo’s bristles scrub on time scales similar to that of other power toothbrushes - hundreds of times a second.

Thanks to the ultrasound-activated bubbles, the Ultreo also removes plaque bacteria where the ultrasound and dental slurry intersect, including where the bristles may not reach.




We ve come a long way
we’ve come a long way

vs

  • a testimony to the initial vision, the initially applied resources and alacrity of SAP/APL/Neurosurgery/Pediatric Dentistry/Periodontology/Public Health, and the subsequent and considerable effort and expertise utilized at Ultreo, along with continuing efforts of UW.



Ultrasound from a stationary brush rapidly removes a line of plaque bacteria
ultrasound from a stationary brush rapidly removes a ‘line’ of plaque bacteria.

  • Artificial teeth with bacteria dyed pink before (left) and after (right) application of ultrasound without bristle contact. Discrete bacteria colonies along a band stretching from lower left to upper right were removed by the ultrasound activated bubbles, in a shape corresponding to the shape of ultrasound emitted from the face of the stationary brush head.


Plaque bacteria removal via combined sonic ultrasound processes
plaque bacteria removal via combined sonic & ultrasound processes

  • Artificial teeth with bacteria dyed pink before (left) and after (right) treatment with a sonically vibrating brush head that emitted ultrasound in the presence of sonically produced bubbles, 2-3 mm from the artificial teeth. Discrete bacteria colonies were reduced or removed across the entire tooth surface after only 5 seconds of application of the prototype.


Sonic ultrasound versus sonic only
sonic & ultrasound versus sonic only processes

  • Artificial teeth with bacteria dyed pink before (above) and after (below) treatment with (AA’) a sonically vibrating brush head that emitted ultrasound in the presence of sonically produced bubbles or (BB’) a popular power toothbrush, each acting 2-3 mm from the artificial teeth. Bacteria were removed across the entire tooth surface after only 5 seconds of application of the prototype.


Uw apl cie invention to start up jack gallagher pierre mourad

yes!


Partnership lessons
partnership lessons processes

  • assuming sufficient technical skills, it is the character of the people with whom you work that matters the most.

  • start your research with the clinical problem in mind.

  • be open to new perspectives and to new knowledge.

  • appreciate the opportunities afforded by serendipity and be willing to act, quickly!, in response to those opportunities.

  • surround yourself with (interdisciplinary) people who sufficiently interact and are open to the fruits of those interactions.

  • make sure your environment facilitates and nurtures those interactions.


Uw apl cie invention to start up jack gallagher pierre mourad

Questions? processes