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The Polio Eradication and Endgame Strategic Plan. Part 1: Technical Rationale for IPV Introduction and OPV Withdrawal. GPEI Accomplishment Significant Decline in Paralysis Due to WPVs, 1988 to 2013*. Poliovirus Types. IPV.

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The Polio Eradication and Endgame Strategic Plan


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  1. The Polio Eradication and Endgame Strategic Plan

  2. Part 1: Technical Rationale for IPV Introduction and OPV Withdrawal

  3. GPEI Accomplishment Significant Decline in Paralysis Due to WPVs, 1988 to 2013*

  4. Poliovirus Types

  5. IPV

  6. Number of Cases of cVDPV-related Polio Exceeds the Number of Cases of WPV

  7. Polio Eradication and Endgame Strategic Plan 2013 to 2018

  8. Polio Eradication and Endgame Strategic PlanObjectives

  9. Objective 2Strengthen Immunization Systems, Introduce IPV, and Withdraw OPV

  10. SAGE Recommendations for the Planned Use of IPV

  11. Introducing at Least 1 Dose of IPV Before the tOPV → bOPV SwitchRationale: Improve Global Population Immunity

  12. Individual Protection Against IPV-induced Paralytic Disease Reducing the Risks

  13. Individual Protection Against IPV-induced Paralytic Disease Reducing the Risks

  14. Individual Protection Against IPV-induced Paralytic Disease Reducing the Risks

  15. Poliovirus Shedding in IPV vs OPV After Virus Vaccine Challenge

  16. IPV and Polio Eradication

  17. Recommended IPV ScheduleKey Points

  18. Programmatic Implications of IPV Introduction

  19. Global Introduction of IPV

  20. Introducing IPV in 124 CountriesA Coordinated, Multipartner Effort

  21. IPV Vaccine DemandForecast and Supply

  22. IPV Presentations and Formulations

  23. IPV Prices for Supply Through UNICEF (2014 to 2018)

  24. GAVI Support for IPVGAVI Alliance Board of Director Decisions, November 2013*

  25. Administration of IPV

  26. Advantages of Administering Multiple Injections at Same Visit

  27. IPV Is Temperature Sensitive

  28. IPV Impact of 1-dose Vial on Central-level Cold Chain in DR Congo Is Limited

  29. IPV Multidose Vials

  30. Technical and Communication Resources for Planning and IPV Introduction

  31. Considerations for Planning and LogisticsSummary

  32. Abbreviations

  33. Abbreviations (cont)

  34. References

  35. References (cont)

  36. References (cont)