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Tetracycline

C. A. A. A. U. A. A. A. A. G. U. A. U. G. A. U. A. C. C. A. A. C. U. C. A. A. A. G. C. C. C. C. C. G. C. C. G. C. G. U. C. A. G. A. A. U. U. C. A. C. C. U. U. U. G. G. C. C. A. A. A. C. C. U. G. U. A. A. G. G. C. C. C. U. U.

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Tetracycline

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  1. C A A A U A A A A G U A U G A U A C C A A C U C A A A G C C C C C G C C G C G U C A G A A U U C A C C U U U G G C C A A A C C U G U A A G G C C C U U G C C C A G C C C G C G U C A G A A U U C A C C U U U G G A G G U G S9 G = 23.8 kcal/mol C A C C A U G G U G A G C A A U C U G G U A C C A C U C G U U C 5’ G C U C Tetracycline A G = 10.2 kcal/mol C 3’ C A A U A A A A A A G G U G U C A C C A U G A A G G U A C 3’ C C 5’ A U G G U A C C A C U C G U U A U A G C A CC A U G G U G A G C A A G G G G C G AAAAn cap C C G 3’ 5’ Supplementary Figure 4 Sequence and structural switching of a tetracycline-responsive Venus (YFP) regulator, s9, and its target mRNA. On s9, the antisense sequence is indicated in red; switching aptamer stem sequence is indicated in blue, the stability of switching stem is indicated. On the target mRNA, the start codon is indicated in green.

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