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Evolution. Genes. GDE. Development. Experience. Thinking about the Biology of Behavior. Homersapien. Current Organism. Current Situation. Current Behavior. Biopsychology – the scientific study of the biology of behavior (Dewsbury, 1991). Psychobiology Behavioral biology

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Thinking about the Biology of Behavior


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    1. Evolution Genes GDE Development Experience Thinking about the Biology of Behavior Homersapien Current Organism Current Situation Current Behavior

    2. Biopsychology – the scientific study of the biology of behavior (Dewsbury, 1991). • Psychobiology • Behavioral biology • Behavioral neuroscience • Physiological psychology  It denotes a biological approach to the study of psychology (the scientific study of behavior).

    3. “Although it is not possible to specify the exact date of biopsychology’s birth, the publication of The Organization of Behavior in 1949 by Donald Hebb played a key role in it’s emergence.”

    4. Biopsychology is an integrative discipline of neuroscience • Neuroanatomy – structure of the nervous system • Neurochemistry – chemical basis of neural activity • Neuroendocrinology – interactions between the nervous system and the endocrine system • Neuropathology – nervous system disorders • Neuropharmacology – effects of drugs on neural activity • Neurophysiology – functions and activities of the nervous system

    5. Research Dimensions of Biopsychology • Human and Nonhuman Subjects • Experiments and Nonexperiments • Pure and Applied Research

    6. Advantages of using Human Subjects: • Follow instructions • Report subjective experiences • Cost effective • Human brains

    7. Evolutionary continuity

    8. Qualitatively similar but quantitatively different Sphere Surface Area = 4 •π • r² Sphere Volume = 4/3 •π • r³ Brain with a medial-lateral (M-L) radius of 2 cm (rat): surface area = 4 x 3.14 x 4 = 50.24 volume= (1.33x3.14) 4.1866 x (23) 8 = 33.49 surface area/volume ratio = 1.50 Brain with a M-L radius of 6.5 cm (human): surface area = 4 x 3.14 x 42.25 = 530.66 volume= (1.33x3.14) 4.1866 x (6.53) 274.625 = 1149.76 surface area/volume ratio = 0.46

    9. Advantages of using Animal Subjects: • Simple systems approach • Comparative approach • Ethical reasons • Pre-clinical research

    10. Symphonic inspirationhttp://www.pbs.org/wgbh/nova/sciencenow/0304/01.html

    11. Animal Research and Disease

    12. Research Designs Used in Biopsychology • Experimental studies • Quasi-experimental studies • Case studies

    13. Experimental studies • Establish cause  effect relations • Essential to scientific discovery • Are paradoxically very simple

    14. Elements of the Experiment • Two or more conditions • Between- or within-subjects design • Independent variable • Dependent variable

    15. Example of an Experimentbased on the Coolidge effect The story: President Calvin Coolidge and his wife were visiting a poultry farm. The first lady asked the farmer how so many eggs were produced with only a few roosters around. The farmer answered “each roosters performs his duty dozens of times each day.” The first lady said “perhaps you should point that out to the president…”

    16. Example of an Experimentbased on the Coolidge effect The story continued… Then President Coolidge said, “But does each rooster service the same hen?” The farmer replied “No, there are many hens for each rooster.” “Perhaps you could point that out to Mrs. Coolidge,” replied the President.

    17. Example of an ExperimentLester & Gorzalka (1988) Problem: the Coolidge effect had only been demonstrated in males (hamsters); attempts with females were unsuccessful. Hypothesis: Studies with females were confounded by the fact that their male partners get fatigued so quickly. Solution: Use more male partners to compensate for the confound of male sexual fatigue.

    18. Lester & Gorzalka (1988): Experimental Design Male # 1  Female # 1 Male # 2  Female # 2 Male # 1 & 2  rest Male # 3  Female # 1 (fatigue) One of two tests were conducted Female # 1 Male # 1 (familiar) Female # 1 Male # 2 (unfamiliar)

    19. Lester & Gorzalka (1988): Experimental Design Dependent Measure: The amount of time female # 1 displayed Lordosis – rodent form of sexual receptivity indicated by an arched-back, rump-up and tail-diverted posture)

    20. Lester & Gorzalka (1988): Results:

    21. Quasiexperimental studies • Studies of groups of subjects exposed to conditions in the real world • Not real experiments as potential confounded variables have not been controlled

    22. Quasiexperimental studies • Poorly educated • Prone to accidental head injury • Likely to use other drugs • Likely to have poor diets

    23. Case studies • Case studies focus on a single individual, such as Jimmie G. • Usually more in-depth than other approaches, but may not be generalizable • Generalizability – the degree to which results can be applied to other cases

    24. Pure and Applied Studies • Pure research – conducted for the purpose of acquiring knowledge • Applied research – intended to bring about some direct benefit to humankind • Some research projects may have elements of both

    25. Divisions of Biopsychology • Six major divisions • Each has a different approach, but there is much overlap • Physiological psychology, psychopharmacology, neuropsychology, psychophysiology, cognitive neuroscience, comparative psychology

    26. Divisions of Biopsychology • Physiological psychology • Neural mechanisms of behavior • Direct manipulation of the brain • Psychopharmacology • Effects of drugs on the brain • Neuropsychology • Brain damage in humans

    27. Divisions of Biopsychology • Psychophysiology (not psychopsychology) • Relation between physiological activity and psychological processes • Cognitive neuroscience • Neural bases of cognition • Comparative psychology • Comparing different species to understand evolution, genetics, and adaptiveness of behavior

    28. Converging Operations Using multiple approaches to address a single question • Korsakoff’s syndrome – a condition characterized by severe memory loss and most commonly seen in alcoholics • Is Korsakoff’s the result of the toxic effects of alcohol on the brain?

    29. Converging Operations • Case studies: • Jimmie G. – an alcoholic with Korsakoff’s • Korsakoff’s is also seen in malnourished persons who had little or no alcohol • Experiments: • Thiamine-deficient rats exhibit memory deficits • Alcohol accelerates the development of brain-damage in thiamine-deficient rats

    30. Converging Operations • Korsakoff’s syndrome is the result of thiamine deficiency, but the damage is accelerated by alcohol • By exploring the possible causes of Korsakoff’s using multiple approaches (converging operations) stronger conclusions can be reached.