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The Influenza Program of the WHO - Chest Specialist in Jaipur Dr Sheetu Singh<br>www.drsheetusingh.com
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The Influenza Program of the WHO • WHO advice on Influenza vaccine composition for NH seasons 2016/17: • A/California/7/2009 (H1N1)pdm09-like virus • A/Hong Kong/4801/2014 (H3N2)-like strain • B/Brisbane/60/2008-like strain February each year: WHO decides for NH winter September each year: WHO decides for SH winter NH: Northern Hemisphere; SH: Southern Hemisphere Source: http://www.who.int/influenza/vaccines/virus/recommendations/2015_16_north/en/ as accessed on 16th Nov 2015, at 2:08pm
Types of Inactivated Influenza Vaccines http://www.ifpma.org/resources/influenza-vaccines/influenza-vaccines/about-influenza-vaccine.html Split Vs Subunit Dr SS
Living virus particle Membrane proteins(hemagglutinin and neuraminidase) Lipid membrane Core with active RNA Live vaccines Attenuation Inactivated vaccines Ultra-centrifugationinactivation Cold-adapted vaccine Whole virus vaccine Influenza vaccine types Source: Wood JM, Williams MS (1998) History of inactivated influenza vaccines. In: Nicholson KG, Webster RG, Hay AJ, editors. Textbook of influenza. Oxford: Blackwell Science. 317–323
Organic Solvent Detergents Split vaccine 2nd generation Subunit vaccine (rosettes) 3rd generation Influenza vaccine types Cold-adapted vaccine Whole virus vaccine, 1st generation Source: Wood JM, Williams MS (1998) History of inactivated influenza vaccines. In: Nicholson KG, Webster RG, Hay AJ, editors. Textbook of influenza. Oxford: Blackwell Science. 317–323
Split vaccine 2nd generation Subunit vaccine (rosettes) 3rd generation Liposome Adjuvant Squalene These particles in virosomal vaccine have fusion activity resulting in T-cell response MF59 vaccine Influenza vaccine types Source: Wood JM, Williams MS (1998) History of inactivated influenza vaccines. In: Nicholson KG, Webster RG, Hay AJ, editors. Textbook of influenza. Oxford: Blackwell Science. 317–323