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Stem Cell and Bone Marrow | Dr. David Greene Arizona

In this presentation, Dr. David Greene Arizona discusses Stem Cells and Bone Marrow. A stem cell or bone marrow transplant replaces damaged blood cells with healthy ones. It can be used to treat conditions affecting the blood cells, such as leukaemia and lymphoma.

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Stem Cell and Bone Marrow | Dr. David Greene Arizona

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  1. STEM CELL AND BONE MARROW Dr. David Greene Arizona

  2. Stem cells are special cells produced by bone marrow (a spongy tissue found in the centre of some bones) that can turn into different types of blood cells. • The 3 main types of blood cell they can become are: • red blood cells – which carry oxygen around the body • white blood cells – which help fight infection • platelets – which help stop bleeding

  3. WHY ARE STEM CELL TRANSPLANTS CARRIED OUT? Stem cell transplants are used to treat conditions in which the bone marrow is damaged and is no longer able to produce healthy blood cells. Transplants can also be carried out to replace blood cells that are damaged or destroyed as a result of intensive cancer treatment.

  4. CONDITIONS THAT STEM CELL TRANSPLANTS CAN BE USED TO TREAT INCLUDE: • severe aplastic anaemia (bone marrow failure) • leukaemia – a type of cancer affecting white blood cells • lymphoma – another type of cancer affecting white blood cells • myeloma – cancer affecting cells called plasma cells • certain blood, immune system and metabolic disorders – examples include sickle cell anaemia, thalassaemia, severe combined immunodeficiency (SCID) and Hurler syndrome

  5. A stem cell transplant will usually only be carried out if other treatments have not helped, the potential benefits of a transplant outweigh the risks and you're in relatively good health, despite your underlying condition.

  6. WHAT DOES A STEM CELL TRANSPLANT INVOLVE? A stem cell transplant can involve taking healthy stem cells from the blood or bone marrow of one person – ideally a close family member with the same or similar tissue type (see below) – and transferring them to another person. This is called an allogeneic transplant. It's also possible to remove stem cells from your own body and transplant them later, after any damaged or diseased cells have been removed. This is called an autologous transplant.

  7. A STEM CELL TRANSPLANT HAS 5 MAIN STAGES. THESE ARE: • Tests and examinations – to assess your general level of health • Harvesting – the process of obtaining the stem cells to be used in the transplant, either from you or a donor • Conditioning – treatment with chemotherapy and/or radiotherapy to prepare your body for the transplant • Transplanting the stem cells • Recovery

  8. Thank You

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