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Herpesviridiae. Crista Wagner. Herpesviridae. double-stranded DNA genome enveloped 150-200 nm. Herpesviridae Taxonomy. Herpesviridae is a viral FAMILY genera of note Simplexvirus oral & genital herpes Varicellovirus chicken pox & shingles Cytomegalovirus immunocompromised individuals.

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Herpesviridiae

Crista Wagner

herpesviridae
Herpesviridae
  • double-stranded DNA genome
  • enveloped
  • 150-200 nm
herpesviridae taxonomy
Herpesviridae Taxonomy
  • Herpesviridae is a viral FAMILY
  • genera of note
    • Simplexvirus
      • oral & genital herpes
    • Varicellovirus
      • chicken pox & shingles
    • Cytomegalovirus
      • immunocompromised individuals
herpesviridae characteristics
Herpesviridae Characteristics

~100 known

named for spreading (herpetic) look of cold sores

alternating active & latent infection

  • latent in nerve cells
  • active in epithelial tissue
  • no genome integration
hsv infection of the neonate
HSV Infection of the Neonate

1/3000 US deliveries

70% are HSV-2

disease manifestation

skin, eye & mouth disease

skin lesions

mortality rate 0%

encephalitis

central nervous system

mortality rate 15%

disseminated infection

central nervous system

multiple organ systems

mortality rate 60%

antiviral therapy (acyclovir)

my questions and answers
My Questions and Answers

Question: What is the family Herpesviridae named for?

Answer: The spreading look of cold sores

No, no. Never, never do you want to have this slide as part of your presentation!!!

herpesviridae characteristics9
Herpesviridae Characteristics

~100 known

named for spreading (herpetic) look of cold sores

alternating active & latent infection

latent in nerve cells

active in epithelial tissue

no genome integration

THIS is how you could answer questions as part of your presentation…

Use animations for emphasis.