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Understanding Crohn's Disease: Symptoms, Complications, and Diagnosis

Crohn's disease is a chronic inflammatory bowel disease that causes severe digestive issues, including diarrhea, abdominal pain, and fatigue. It may also lead to complications such as arthritis, liver disease, and various skin disorders affecting up to 25% of patients. Common symptoms include blood in stool, weight loss, and bowel obstructions. Diagnosis involves lab tests showing elevated ESR and CRP, along with endoscopic and radiographic evaluations. Understanding Crohn's disease is crucial for managing its extensive health impacts and improving quality of life for those affected.

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Understanding Crohn's Disease: Symptoms, Complications, and Diagnosis

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  1. Crohn’s disease

  2. IDIOPATHIC INFLAMMATORY BOWEL DISEASE - The illnesses in this category, which include Crohn’s disease and chronic ulcerative colitis, are among the most common organic causes of chronic diarrhea in adults and range in severity from mild to fulminant and life-threatening. They may be associated with uveitis, polyarthralgias, cholestatic liver disease (primary sclerosingcholangitis), and various skin lesions (erythemanodosum, pyodermagangrenosum)

  3. There are many complications that can occur with Inflammatory Bowel Disease (IBD) including arthritis, liver disease, nutritional disorders, anemia, and skin disorders. Skin disorders are a fairly common problem, and may affect up to 25 percent of people who suffer from IBD. One type of skin disorder that may occur in IBD is pyodermagangrenosum.

  4. Crohn’s disease • Lab abnormalities: elevated ESR and CRP • In more severe cases: hypoalbuminemia, anemia, and leukocytosis • Endoscopic feature: rectal sparing, aphthous ulceration, fistulas, and skip lesions, continuous disease, “Cobblestoning, granuloma on biopsy • Clinical: gross blood in stool, mucus, systemic symptoms, pain, abdominal mass, significant perineal disease, fistulas, small-intestine obstruction, colonic obstruction, response to antibiotics, recurrence after surgery, ANCA-positive, ASCA-positive • Radiographic: small bowel significantly abnormal, abnormal terminal ileum, segmental colitis, asymmetric colitis, stricture *the patient did not have any of the signs and symptoms mentioned above and therefore does not have Crohn’s disease

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