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is the permanent cessation of menstruation resulting from loss of ovarian follicular activity. It can only be determined after 12 months\' spontaneous amenorrhoea. Mean age is 51 years. . Menopause. is the period of time in which the ovaries are beginning to fail, where endocrine, biological, and clinical changes are seen. It ends with the final menstrual period.Length of the transition is approximately 4 years .

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