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The Digestive System Chapter 23 – Lecture Notes. to accompany Anatomy and Physiology: From Science to Life textbook by Gail Jenkins, Christopher Kemnitz, Gerard Tortora. Chapter Overview. 23.1 Gastrointestinal (GI) Tract 23.2 Accessory Organs of the Head 23.3 Swallowing 23.4 Stomach
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The Digestive SystemChapter 23 – Lecture Notes to accompany Anatomy and Physiology: From Science to Life textbook by Gail Jenkins, Christopher Kemnitz, Gerard Tortora
Chapter Overview 23.1 Gastrointestinal (GI) Tract 23.2 Accessory Organs of the Head 23.3 Swallowing 23.4 Stomach 23.5 Accessory Organs of the Abdomen 23.6 Small Intestine 23.7 Large Intestine 23.8 Phases of Digestion 23.9 Food Molecules 23.10 Metabolism
Essential Terms digestion • process of mechanically or chemically breaking down food absorption • passage of small molecules into blood and lymph digestive system • organs which carry out process of digestion and absorption metabolism • all the chemical reactions of the body
Introduction Digestive System • Composed of GI tract and accessory organs • Breaks down ingested food for use by the body • Digestion occurs by mechanical and chemical mechanisms • Excretes waste products or feces through process of defecation
GI Tract / Alimentary Canal • Continuous tube from mouth to anus • Mouth • Pharynx • Esophagus • Stomach • Small intestine • Large intestine
Accessory Digestive Organs • Provide mechanical and chemical mechanisms to aid digestion • Teeth • Tongue • Salivary glands • Liver • Gallbladder • Pancreas
Functions of Digestive System • Ingestion • Secretion • Mixing and propulsion • Motility • Digestion • Mechanical and chemical • Absorption • Defecation
Layers of GI Tract • Same in all areas of GI tract • From deep to superficial: • Mucosa • Submucosa • Muscularis • Serosa
Layers of GI Tract • Mucosa • Epithelium • Type varies • Lamina propria – areolar connective tissue • MALT – mucus-associated lymphatic tissue • Muscularis mucosae – smooth muscle • Submucosa • Areolar connective tissue • Blood and lymphatic vessels • Neurons – submucosal plexus
Layers of GI Tract • Muscularis • Skeletal and smooth muscle • Neurons – myenteric plexus • Serosa • Areolar and simple squamous epithelium • Visceral peritoneum
Peritoneum • Mesothelium • Parietal peritoneum • Visceral peritoneum • Peritoneal cavity • Retroperitoneal
Folds of Peritoneum • Greater omentum • Adipose tissue • Falciform ligament • Liver to anterior abdominal wall • Lesser omentum • Mesentery • Small intestine to posterior abdominal wall • Mesocolon
Neural Innervation of GI Tract • Regulated by autonomic nervous system • Enteric division • Myenteric plexus / plexus of Auerbach • Submucosal plexus / plexus of Meissner • Able to function independently from rest of nervous system • Linked to CNS by extrinsic sympathetic and parasympathetic nerves • Sympathetic nerves decrease GI secretions & motility • Parasympathetic nerves increase GI secretion and motility
Mouth Parts of Digestive System • Mouth formed by several parts: • Cheeks • Lips / labia • Labial frenulum • Orbicularis • Vestibule • Oral cavity proper • Fauces • Hard and soft palate • Uvula • Palatoglossal and palatopharyngeal arch
Tongue • Skeletal muscle and mucous membrane • Helps form floor of oral cavity • Extrinsic muscles • Intrinsic muscles • Lingual frenulum • Papillae • Fungiform • Filiform • Circumvallate • Foliate • Lingual glands • Lingual lipase
Salivary Glands • Release saliva to oral cavity • 3 pairs of salivary glands • Parotid • Submandibular • Sublingual
Composition of Saliva • 99.5 % water • 0.5% other solutes • Ions • Mucus • Immunoglobulin A • Enzymes • Salivation controlled by autonomic nervous system • Stimulated by various mechanisms
Teeth • External regions • Crown • Root • Neck • Internal components • Enamel • Dentin • Cementum • Pulp cavity • PulpRoot canals • Apical foramen
Teeth • Dentitions • Deciduous teeth – first set • Permanent teeth – secondary • Carry out mechanical digestion by mastication • Creates bolus • Salivary amylase • Breakdown starch • Lingual lipase • Breakdown triglycerides
Pharynx • Composed of skeletal muscle • Lined by mucous membrane • Nasopharynx • Oropharynx • Laryngopharynx
Esophagus • Collapsible muscular tube through esophageal hiatus of diaphragm • Mucosa • Submucosa contains areolar connective tissue • Muscularis • Skeletal muscle • Upper and lower esophageal sphincter • Adventitia • Attaches esophagus to nearby structures • Secrets mucus and transports food
Deglutition • Stages of swallowing • Voluntary • Mouth to oropharynx • Pharyngeal • Deglutition center in medulla oblongata and pons • Closing of epiglottis • Involuntary • Esophageal • Involuntary • Peristaltic contractions
Stomach • Serves as mixing chamber and storage area for ingested food • Rugae allow for increased volume • 4 main regions • Cardia • Fundus • Body • Pylorus • Pyloric antrum and canal • Pyloric sphincter • Lesser and greater curvatures
Stomach Histology • Mucosa • Surface mucous cells • Lamina propria • Muscularis mucosae • Gastric glands and pits • Parietal cells • Chief cells • G cells • Submucosa – areolar connective tissue • Muscularis • 3 layers of smooth muscle • Serosa
Mechanical and Chemical Digestion • Mixing waves caused by peristaltic movement • Chyme released in process of gastric emptying • Proton pumps bring H+ into the lumen • Carbonic anhydrase forms carbonic acid to provide H+ and bicarbonate ions (HCO3-)
Mechanical and Chemical Digestion • Chemical digestion stimulated by nervous system • Parasympathetic neurons release acetylcholine • Works with gastrin • HCl released in presence of histamine • Pepsin begins digestion of proteins • Stomach protected by alkaline mucus secretion • Gastric lipase digests triglycerides • Few molecules absorbed by stomach • Water, ions, short-chain fatty acids, alcohol