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American Chemical Society

Pharmaceutical Process Development and ACS Journal Editorship; not a typical career in chemistry??

Jaan Pesti.Principal Scientist Associate EditorBristol-Myers Squibb Co American Chem SocProcess Res & Dev Organic Process R & DNew Brunswick, NJ Yardley, PA

route to become a process chemist the early years

Route to become a process chemist; the early years

  • Bachelor of Arts
  • Long Island University – Brooklyn Center
  • Pharmacy
  • Organic chemistry
  • Joined ACS in 1974
    • C & E News - eye on what is happening
    • Job surveys
    • Belong to the guild
  • Ph.D in Organic Chemistry
  • Columbia University
    • What if things don’t work out? Be

flexible!

    • Synthetic chemistry
    • Enjoyed ‘writing up,’ first clue for my future
route to become a process chemist the early years1

Route to become a process chemist; the early years

  • Post-doctoral studies
  • University of California at Berkeley
    • Synthetic organic chemistry
    • Supervision of undergraduate
    • Make connections
    • How to ‘sell’ yourself
where have i been since school

Where have I been since school??

  • Worked for four companies
    • Dupont Chemical Co
    • Dupont Merck
    • Dupont Pharmaceuticals
    • Bristol-Myers Squibb
  • Moved five times
    • Dupont Experimental Station
    • Dupont Chambers Works
    • X Station again
    • Chambers Works again
    • BMS Princeton site
    • BMS New Brunswick site
  • But have always been primarily a bench chemist!
    • Know what you are!
what do i do at bristol myers squibb

What do I do at Bristol Myers Squibb??

  • figure out how to scale up processes for new

pharmaceutical agents.

- safety

- cost

- speed

- future

  • organize and prepare multikilogram batches for a

variety of studies, including clinical.

  • instruct and oversee outside vendor preparations.
  • anticipate future needs.
  • preparation for regulatory documents, which leads

to……………………..

now for something completely different

Now for something completely different

Associate Editorship of Org Process Res & Dev

background

  • take control of one’s own career
  • started publishing & presenting in 1998
    • ACS Nat mtgs, ACS journals
  • became OPRD reviewer in 2006
  • joined OPRD Editorial Advisory Board in 2007
  • became OPRDAssoc. Editor in 2008
what is the role of an assoc editor

What is the role of an Assoc. Editor??

  • assign manuscripts for review
  • oversee review process
  • review all manuscripts for content, style, etc
  • make decision to accept, reject or revise
  • make final acceptance
  • recruit talent for OPRD
  • market OPRD
  • provide guidance for future direction of journal
  • in general, whatever will improve the service of OPRD to our readers
secrets to being published

Secrets to being published!

  • first, do something worth publishing
  • what is the theme of your publication
  • feel free to ask an Assoc Editor
  • before you start writing, what journal are you

targeting.

  • get a fast first draft down on paper
  • then rewrite, rewrite, rewrite, rewrite
  • but write in good English
  • write dynamically and avoid the passive voice
  • check the ACS style guide
  • ask a colleague to critique your manuscript
  • be accurate
  • avoid silly mistakes
  • cite OPRD frequently