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Updated Coagulation Cascade

Extrinsic Pathway. VII. Vascular injury. VIIa + TF. Fibrin polymers Insoluble fibrin. Fibrin polymers Soluble fibrin. Fibrinogen. Fibrin monomer. Updated Coagulation Cascade. Correction: Walsh PN. Biochemistry 2007,Nov 6; 46(44): 12886-12887. Intrinsic Pathway. surface HMWK PK.

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Updated Coagulation Cascade

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  1. Extrinsic Pathway VII Vascular injury VIIa + TF Fibrin polymers Insoluble fibrin Fibrin polymers Soluble fibrin Fibrinogen Fibrin monomer Updated Coagulation Cascade Correction: Walsh PN. Biochemistry 2007,Nov 6; 46(44): 12886-12887 Intrinsic Pathway surface HMWK PK XII XIIa XI XIa HMWK Ca2+ Ca2+ IX IXa Ca2+ PL VIII VIIIa X Xa X V Va Ca2+ PL XIII prothrombin thrombin fibrin XIIIa

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