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Explore the innovative DNA nanomechanical translation machine, its principles of operation, possible products, and relationship to traditional components. Learn about its purification, ligation, and analysis, sequencing results, and visualized applications in polymer unit organization and DNA walking biped. Discover how all combinations work and visualize the device and sidewalk schematic.
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Two States of the Array B. Ding & N.C. Seeman,Science314, 1583-1585 (2006).
Transitions in the Array B. Ding & N.C. Seeman,Science314, 1583-1585 (2006)..
Transitions in the Array (Zoom) B. Ding & N.C. Seeman,Science314, 1583-1585 (2006).
Programming an Array for Assembly A. Carbone & N.C. Seeman, Proc. Nat. Acad. Sci. (USA)99 12577-12582 (2002).
A Ribosome-Like Device:A DNA Nanomechanical Translation MachineShiping Liao
A Drawing of the Device Fixed Sticky Ends Movable Sticky Ends Movable Sticky Ends Liao, S. & Seeman, N.C. (2004), Science 306, 2072-2074.
Principles of Operation Liao, S. & Seeman, N.C. (2004), Science 306, 2072-2074.
Possible Products Liao, S. & Seeman, N.C. (2004), Science 306, 2072-2074.
Relationship to Traditional Components DX Molecules Correspond to Aminoacyl tRNA Molecules Anticodon Equivalent Liao, S. & Seeman, N.C. (2004), Science 306, 2072-2074.
Purification, Ligation & Analysis Liao, S. & Seeman, N.C. (2004), Science 306, 2072-2074.
Sequencing Result * All Combinations Work Liao, S. & Seeman, N.C. (2004), Science 306, 2072-2074.
VisualizedApplication Polymer Unit DX Molecule Organized Polymers
Schematic of the Device and Sidewalk Sherman, W.B. & Seeman, N.C. (2004), NanoLett. 4, 1203-1207.