Lecture 28. Quiz Friday on Beta-Oxidation of Fatty acids Electron transport chain Electron transport cofactors ATPase. Formation of a trans double bond by dehydrogenation by acyl-CoA dehydrogenase (AD).
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Cofactors of the electron transport chain electron carriers.
Iron-sulfur clusters electron carriers.
Can accept or donate 1 or 2 e-
Coenzyme Q’s hydrophobic tail allows it to be soluble in the inner membrane lipid bilayer.
Figure 22-21a electron carriers. Visible absorption spectra of cytochromes. (a) Absorption spectrum of reduced cytochrome c showing its characteristic a, b, and g (Soret) absorption bands.
Figure 22-21b electron carriers. The three separate bands in the spectrum of beef heart mitochondrial membranes indicate the presence of cytochromes a, b, and c.
Figure 22-22b electron carriers. Porphyrin rings in cytochromes. (b) Axial liganding of the heme groups contained in cytochromes a, b, and c are shown.
NADH + H electron carriers.+
Succinate electron carriers.
CoQH electron carriers.2
cyt c red
cyt c ox
cyt b ox
cyt b red
cyt c electron carriers.red
cyt a ox
cyt c ox
cyt a red
Inhibitors of Oxidative Phosphorylation electron carriers.
Chemiosmotic Theory electron carriers.
ATP Synthase electron carriers.
Racker & Stoeckenius confirmed Mitchell’s hypothesis using vesicles containing the ATP synthase and bacteriorhodopsin
Transport of ATP, ADP and Pi Inner Membrane
Uncouplers Inner Membrane