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Presentation objectives. Provide an overview of Cochrane Collaboration Demonstrate The Cochrane Library Invite participation. Cochrane Collaboration.

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presentation objectives
Presentation objectives
  • Provide an overview of Cochrane Collaboration
  • Demonstrate The Cochrane Library
  • Invite participation
cochrane collaboration
Cochrane Collaboration
  • An international organisation that aims to help people make well-informed decisions about healthcare by preparing, maintaining and promoting the accessibility of systematic reviews of the effects of health care interventions.
archie cochrane
Archie Cochrane

“It is surely a great criticism of our profession that we have not organised a critical summary, by specialty or subspecialty, adapted periodically, of all relevant randomised controlled trials.”

principles
Principles
  • Collaboration
  • Building on the enthusiasm of individuals
  • Avoiding duplication
  • Minimising bias
principles7
Principles
  • Keeping up to date
  • Striving for relevance
  • Promoting access
  • Ensuring quality
  • Continuity
cochrane collaboration goals
Cochrane Collaboration goals
  • To ensure high quality, up-to-date systematic reviews are available across a broad range of health care topics
  • To promote access to Cochrane reviews
cochrane collaboration goals9
Cochrane Collaboration goals
  • To develop an efficient, transparent organisational structure and management system for the Cochrane Collaboration
  • To achieve sustainability of the Cochrane Collaboration
systematic review

Systematic review

Systematic review

Systematic review
  • Structured process involving several steps:
    • Well formulated question
    • Comprehensive data search
    • Unbiased selection and abstraction process
    • Critical appraisal of data
    • Synthesis of data
cochrane collaboration11
Cochrane Collaboration

Collaborative Review Groups

Centres

Steering Group

Methods Groups

Fields

The Consumer Network

cochrane collaboration12
Cochrane Collaboration

Collaborative Review Groups

Centres

Steering Group

Methods Groups

Fields

The Consumer Network

cochrane centres

Cochrane Centres

Canadian

Nordic

San Francisco

German

UK

Dutch

French

Iberoamerican

Italian

San Antonio

Chinese

New England

Brazilian

South African

Australasian

cochrane centres14
Cochrane Centres
  • Help organise and register review groups
  • Facilitate collaboration among reviewers
  • Provide training and consultation
  • Establish liaisons
  • Promote the Cochrane Collaboration
  • Provide unique contribution
cochrane collaboration15
Cochrane Collaboration

Collaborative Review Groups

Centres

Steering Group

Methods Groups

Fields

The Consumer Network

review groups 48 registered 1 possible
Review Groups48 registered, 1 possible
  • Focus
    • Treatment of disease or health problems
      • Emphasis on clinical outcomes
      • Emphasis on rigorous data
review groups
Acute respiratory infections

Airways

Anaesthesia

Back

Breast cancer

Colorectal cancer

Consumers and communication

Cystic fibrosis and genetic disorders

Dementia & cognitive improvement

Depression, anxiety & neurosis

Developmental, psychosocial and learning problems

Drugs and alcohol

Ear, nose and throat disorders

Effective practice and organisation of care

Epilepsy

Eyes and vision

Fertility regulation

Gynaecological cancer

Heart

Hepato-biliary

Review Groups
review groups18
HIV/AIDS

Hypertension

Incontinence

Infectious diseases

Inflammatory bowel disease

Injuries

Lung cancer

Menstrual disorders and subfertility

Metabolic and endocrine disorders

Movement disorders

Multiple sclerosis

Muskuloskeletal

Musculoskeletal injuries

Neonatal

Neuromuscular disease

Oral health

Pain, palliative and supportive care

Peripheral vascular diseases

Pregnancy and childbirth

Prostatic diseases and urologic cancers

Renal

Schizophrenia

Review Groups
review groups19
Sexually transmitted diseases

Skin

Stroke

Tobacco addiction

Upper gastrointestinal and pancreatic diseases

Wounds

Haematological malignancies (possible)

Review Groups
review group products
Review Group products
  • Reviews
  • Specialised register
review groups21
Review Groups
  • Reviewers
    • International group
    • Review relevant trials on specified health care problems
    • Long-term commitment
slide22

Collaborative Review Group process

Systematic

Reviewer

Systematic

Reviewer

Systematic

Reviewer

Editors

Review Group

Co-ordinator

Systematic

Reviewer

Systematic

Reviewer

Cochrane Database of

Systematic Reviews

review manager revman
Review Manager (RevMan)
  • Cochrane Collaboration software for:
    • Preparing and maintaining protocols and reviews
    • Data analysis
    • Submitting completed reviews to CDSR
revman statistical options
RevMan statistical options
  • Peto Method
    • Odds Ratio
  • Mantel-Haenszel fixed effect and Dersimonian/Laird random effects
    • Odds Ratio, Relative Risk, Risk Difference
    • Weighted and Standardised Mean Differences
the cochrane library
The Cochrane Library
  • The Cochrane Database of Systematic Reviews (CDSR)
  • The Database of Abstracts of Reviews of Effectiveness (DARE)
  • The Cochrane Controlled Trials Register (CCTR)
  • The Cochrane Methodology Register
cochrane collaboration26
Cochrane Collaboration

Collaborative Review Groups

Centres

Steering Group

Methods Groups

Fields

The Consumer Network

fields 9 registered 1 possible
Fields9 registered, 1 possible
  • Represent a population, group, or type of care that overlaps multiple Review Group areas
  • Examples: Primary Health Care, Health Care of Older Adults, Complementary Medicine, Vaccines, Rehabilitation and Related Therapies
methods groups 11 registered 5 possible
Methods Groups11 registered, 5 possible
  • Develop methods and products integral to internal functioning of the Collaboration
  • Develop state of the art methods for systematic reviews
  • Examples: Statistical Methods, Economics, Placebo Effects, Informatics
the consumer network
The Consumer Network
  • Provides consumer input
  • Helps set priorities
  • Helps with dissemination
cochrane collaboration30
Cochrane Collaboration

Collaborative Review Groups

Centres

Steering Group

Methods Groups

Fields

The Consumer Network

steering group
Steering Group
  • Function
    • Policy making body of the Cochrane Collaboration
  • Who
    • Elected representatives of each of the Collaboration entities (Review Groups, Centres, Fields, Methods Groups, the Consumer Network)
summary of the cochrane collaboration
Summary of The Cochrane Collaboration
  • International collaboration
  • Prepares, maintains, and disseminates systematic reviews
  • Diverse internal structure (Review Groups, Centres, Fields, Methods Groups, the Consumer Network)
how to participate
How to participate
  • Join a Collaborative Review Group
  • Join a Field, Methods Group, or the Consumer Network
  • Handsearch a journal
  • Identify or provide funding
future challenges
Future challenges
  • Recruitment of large numbers of reviewers in all areas of health care
  • Clinically useful presentation of the Cochrane Database of Systematic Reviews
  • Efficient and effective communication within the Collaboration
  • Financial solvency of the organisation
the cochrane collaboration36

The Nordic Cochrane Centre

Rigshospitalet, dept 7112

Blegdamsvej 9

DK-2100 Copenhagen Ø

Denmark

Phone: +45 35 45 55 71 FAX: +45 35 45 70 07

E-mail: general@cochrane.dk

The Cochrane Collaboration

For more information: www.cochrane.dk