clinical manifestations of hyperkalemia n.
Download
Skip this Video
Loading SlideShow in 5 Seconds..
Clinical manifestations of hyperkalemia PowerPoint Presentation
Download Presentation
Clinical manifestations of hyperkalemia

Loading in 2 Seconds...

play fullscreen
1 / 6

Clinical manifestations of hyperkalemia - PowerPoint PPT Presentation


  • 407 Views
  • Uploaded on

Clinical manifestations of hyperkalemia. Parham W. et.al. (2006). Hyperkalemia Revisited. Tex Heart Inst J. 33(1):40-47. Clinical manifestations of hyperkalemia. hyperkalemia partially depolarizes the cell membrane.

loader
I am the owner, or an agent authorized to act on behalf of the owner, of the copyrighted work described.
capcha
Download Presentation

PowerPoint Slideshow about 'Clinical manifestations of hyperkalemia' - dani


An Image/Link below is provided (as is) to download presentation

Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.


- - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - -
Presentation Transcript
clinical manifestations of hyperkalemia
Clinical manifestations of hyperkalemia

Parham W. et.al. (2006). Hyperkalemia Revisited. Tex Heart Inst J. 33(1):40-47

clinical manifestations of hyperkalemia1
Clinical manifestations of hyperkalemia
  • hyperkalemiapartially depolarizes the cell membrane.
  • Prolonged depolarization impairs membrane excitability and is manifest as weakness, which may progress to flaccid paralysis and hypoventilation if the respiratory muscles are involved
metabolic acidosis

Clinical manifestations of hyperkalemia

Metabolic Acidosis
  • Hyperkalemia inhibits renal ammoniagenesis and reabsorption of NH4+ in the TALH
  • Net acid excretion is impaired and results in metabolic acidosis

=15

Hyperglycemia400 mg/dL (300≈DKA)

Acid anion - acetoacetate

management
Management
  • Calcium gluconate↓membrane excitability
    • 10 mL of 10% solution infused over 2-3 min
    • Effect seen ECG after 5-10 min (if not-repeat dose)
  • Insulin for K+ shift into cells
    • 10-20 units regular insulin
    • Fall by 0.5-1.5 mmol/L in 15-30 min
management dka
Management (DKA)
  • Replace fluids:
    • 2-3L of 0.9% saline over first 1-3h;
    • subsequently, 0.45% saline at 150-300 mL/h;
    • change to 5% glucose and 0.45% saline at 100-200mL/h when plasma glucose reaches 250 mg/dL
  • Short-acting insulin:IV (0.1 u/kg)
    • then 0.1 u/kg/h by continuous IV infusion
  • Monitor glucose q1-2h
    • electrolytes, anion gap q4h for 1st 24 h
  • Glucose goal is 150-250 mg/dL
    • insulin dec 0.05-0.1u/kg/h
management1
Management
  • Dialysis
    • Intractable acidosis
    • Intractable electrolyte imbalance
    • Intoxication
    • Intractable volume overload
    • Intractable uremia