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PSYCHOPHARMACOLOGY. PSYCHOPHARMACOLOGY. Antipsychotics Antiparkinsonisms Antidepressants Mood stabilizers Sedative Hypnotics Others. Principles of psychopharmacotherapy. The diagnostic assessment is fundamental to our model Pharmacotherapy is insufficient for complete recovery.

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psychopharmacology1
PSYCHOPHARMACOLOGY
  • Antipsychotics
  • Antiparkinsonisms
  • Antidepressants
  • Mood stabilizers
  • Sedative Hypnotics
  • Others
principles of psychopharmacotherapy
Principles of psychopharmacotherapy
  • The diagnostic assessment is fundamental to our model
  • Pharmacotherapy is insufficient for complete recovery.
  • The phase of an illness is of critical importance in terms of the initial intervention and the duration of treatment
  • The risks to benefit ratio must always be considered when developing a treatment strategy
principles of psychopharmacotherapy1
Principles of psychopharmacotherapy
  • Prior personal history of good and bad response to a specific agent usually dictates the first line of choice for a subsequent episode.
  • It is important to target specific symptoms that serves as a marker for the underlying psychopathology.
  • Observe the development of adverse side effects.
indications of antipsychotics
Indications of antipsychotics
  • Brief psychotic disorders
  • Schizophreniform
  • Schizophrenia
  • Schizoaffective Disorders
  • Delusional disorders
  • Psychotic mood disorders
  • Organic psychoses
antipsychotics
Antipsychotics
  • Phenothiazines
    • Aliphatic
      • Chlorpromazine ( Thorazine 25, 50,100mg)
    • Piperidines
      • Thioridazine ( Melleril 50, 100mg )
    • Piperazines
      • Fluphenazine
      • Perphenazine ( Trilafon 4, & 8 mg.)
      • Trifluoperazine ( Stelazine 5 mg.)
      • Mesoridazine ( serentil 10mg.)
antipsychotics1
Antipsychotics
  • THIOXANTHENES
    • Thiothexenes – Navane
    • Zuclophentixol HCl – Clopixol 10, 25mg tab
    • Zuclophentixol decanoate – Clopixol depot
    • Zuclophentixol acetate – Clopixol Acuphase
antipsychotics2
Antipsychotics
  • Butyrophenones

Haloperidol ( Haldol, 1, 2, 5, 10 mg/tab) ( Serenace 5, 10, 20mg/tab )

( Serenace 5mg/ampule )

antipsychotics3
Antipsychotics
  • Benzamides
    • Sulpiride – Dogmatil
    • Amisulpiride - Solian
antipsychotics serotonin dopamine antagonists
AntipsychoticsSerotonin-Dopamine Antagonists
  • Dibenzodiazepines
    • Clozapine - Leponex
  • Thiobenzodiazepines
    • Olanzapine - Zyprexa
  • Benzothiazepines
    • Quetiapine - seroquel
  • Benzisoxasoles
    • Risperidone - Risperdal
  • Benzisothiasole piperazine
    • Ziprasidone - Zeldox
antiparkinsonism
Antiparkinsonism
  • Biperidin HCl – Akineton 2mg.
  • Diphenhydramine – Benadryl 50mg
  • Amantadine – Symmetrel 100mg
  • Benztropine mesylate – Cogentin 2mg
  • Trihexyphenidyl HCl – Artane 2mg
antidepressants
Antidepressants
  • Heterocyclics
  • MAOI’s
  • RIMA
  • Dopamine Agonists
  • SSRI
  • SNRI
antidepressants heterocyclics
AntidepressantsHeterocyclics
  • Tricyclics
    • Imipramine - Tofranil
    • Clomipramine - Anafranil
  • Tetracyclics
    • Maprotiline - Ludiomil
    • Dothiepine – Prothiaden
    • Mirtazapine - Remeron
antidepressants monoamine oxidase inhibitors maoi
AntidepressantsMonoamine Oxidase Inhibitors (MAOI)
  • Increases biogenic amines by inhibiting their degradation
  • Should not be taken with foods w/ tyramine
  • Examples
    • Tranylcypromine ( Parnate )
    • Phenelzine ( Nardil )
    • Iproniazid ( Marsilid )
antidepressants reuptake inhibitor of monoamine oxidase inhibitor type a rima
AntidepressantsReuptake Inhibitor of Monoamine Oxidase Inhibitor type A (RIMA)
  • Moclobemide – Aurorix 150 mg
  • Brofaromine
antidepressants dopamine agonists
AntidepressantsDopamine Agonists
  • Amineptine HCl – Survector 100mg/tab
antidepressants selective serotonin reuptake inhibitors ssri
AntidepressantsSelective Serotonin Reuptake Inhibitors (SSRI)
  • Paroxetine – Paxil, Seroxat 20/tab
  • Fluovoxamine – Luvox, Faverin 50mg/tab
  • Fluoxetine – Prozac 20mg/pulvules
  • Sertraline – Zoloft 50mg/tab
mood stabilizers
Mood Stabilizers
  • Lithium carbonate – Quilonium R 450mg/tab
  • Carbamazepine – Tegretol 200mg/tab
  • Oxcarbazepine – Trileptal 300 & 600mg
  • Depakene – Valproic Acid
  • Divalproate sodium – Epival 250mg/tab
sedative hypnotics
Sedative - Hypnotics
  • Benzodiazepines
  • Imidazopyridines
  • Cyclopyrrolone derivatives
imidazopyridines
Imidazopyridines
  • Zolpidem – Stilnox 10mg/tab
cyclopyrrolone derivative
Cyclopyrrolone derivative
  • Zopiclone – Imovane 7.5mg/tab