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Intracellular Compartments

Intracellular Compartments. ER, Golgi, Endsomes, Lysosomes and Peroxisomes. Endomembrane System. Endoplasmic Reticulum. Of what does the endoplasmic reticulum consist? What distinguishes the rough ER from the smooth ER?. Endoplasmic Reticulum.

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Intracellular Compartments

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  1. Intracellular Compartments ER, Golgi, Endsomes, Lysosomes and Peroxisomes

  2. Endomembrane System

  3. Endoplasmic Reticulum • Of what does the endoplasmic reticulum consist? • What distinguishes the rough ER from the smooth ER?

  4. Endoplasmic Reticulum • How do ER membranes compare with the plasma membrane?

  5. Endoplasmic Reticulum • What cellular processes take place in the smooth ER? • What is aryl hydrocarbon hydroxylase?

  6. Endoplasmic Reticulum • What is the fate of proteins made on the RER? • What happens to proteins before they leave the ER?

  7. Endoplasmic Reticulum • What else takes place in the ER? • How do newly made phospholipids get to other cell organelles?

  8. Golgi Complex • Of what does the Golgi consist?

  9. Golgi Complex • How do the Golgi membranes compare with those of the ER? • What enzymes are associated with this organelle? • How are the different vesicles associated with Golgi distinguished?

  10. Golgi Complex • What two models describe the flow of lipids and proteins through the Golgi complex? • How do anterograde transport differ from retrograde transport?

  11. Golgi Complex • What is glycosylation? • What are the two forms of glycosylation?

  12. Golgi Complex • How does glycosylation take place? • begins in ER • continues in Golgi

  13. Protein Sorting • How are proteins sorted as they move through ER and Golgi?

  14. Protein Sorting • How are lysosomal enzymes targeted? • How do we know this proposed pathway is valid?

  15. Protein Sorting • What evidence supports secretory pathway?

  16. Protein Sorting

  17. Protein Sorting • What is the difference between constitutive and regulated secretion?

  18. Exocytosis and Endocytosis • What is involved in exocytosis? • What appears to trigger this process?

  19. Exocytosis and Endocytosis • What is involved in endocytosis? • What happens to endocytic vesicles?

  20. Exocytosis and Endocytosis • What are the three forms of endocytosis?

  21. Phagocytosis • What kinds of cells carry out phagocytosis?

  22. Receptor-Mediated Endocytosis • How is this process different from phagocytosis?

  23. Clathrin-Independent Endocytosis • What function does this process appear to serve?

  24. Lysosomes • What are some of the characteristics of these organelles?

  25. Lysosomes • How are these organelles formed? • What functions do they serve?

  26. Lysosomes • What is the difference between an early endosome, a late endosome and a lysosome? • Do all late endosomes become lysosomes?

  27. Lysosomes • In what way do lysosomes play key roles in both cell defense and nutrition? • What are residual bodies? • What is the difference between autophagy and autolysis?

  28. Lysosomes • Under what conditions are lysosomal enzymes released outside of the cell? • What causes lysosomal storage diseases?

  29. Peroxisomes • What technique enabled DeDuve to successfully isolate these organelles?

  30. Peroxisomes • What are some of the distinguishing characteristics of this organelle? • How are they identified cytochemically? • What functions are associated with peroxisomes?

  31. Peroxisomes • Why does hydrogen peroxide accumulate in these organelles? • In what way does this organelles contribute to fatty acid oxidation? • From where do these organelles come?

  32. Peroxisomes • What types of unusual peroxisomes are found in plants?

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