hair cell and meddis hair cell model l.
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Hair Cell and Meddis Hair Cell Model - PowerPoint PPT Presentation


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Hair Cell and Meddis Hair Cell Model. Xiaoxiang Gong. Outline. Function of Hair Cells Hair Cell Model – Meddis Model Simulation Result for the Meddis Model Phase Locking. Function of Hair Cell. Meddis Model for Hair Cell. Synaptic cleft Outside the Hair cell. Hair cell.

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Presentation Transcript
outline
Outline
  • Function of Hair Cells
  • Hair Cell Model – Meddis Model
  • Simulation Result for the Meddis Model
  • Phase Locking
meddis model for hair cell
Meddis Model for Hair Cell

Synaptic cleft

Outside the Hair cell

Hair cell

  • Spike Probability is proportional to the amount of transmitter in the synaptic cleft.
simulation result for meddis model from auditory toolbox
Simulation Result for Meddis Model -- from Auditory Toolbox
  • Stimulus: Single tone (1KHz) with amplitude scales on silent background.
  • Spontaneous rate
  • Onset rate: the initial peak value
  • Steady state rate: adaptation level
phase locking
Phase Locking
  • The auditory nerve will tend to fire at a particular phase of a stimulating low-frequency tone (Period Histogram). So the inter-spike intervals tend to occur at integer multiples of the periods of the tone (Inter-spike Interval Histogram).
  • Phase locking depends on the stimulus frequency: with high frequency tones (> 3kHz) phase locking gets weaker.
phase locking period histogram inter spike interval histogram
Phase Locking-- Period Histogram & Inter-spike Interval Histogram

AN fibers fire at integer multiples of the stimulus period, not necessarily on every period

phase locking period histograms from meddis model
Phase Locking-- Period Histograms from Meddis Model
  • Showing a half-wave rectified version of the stimulus
phase locking inter spike interval histograms from meddis model
Phase Locking-- Inter-spike Interval Histograms from Meddis Model
  • AN fibers fire at intervals related to stimulus frequency.

For 1KHz sinusoid input