بسم الله الرحمن ارحيم. LARYNGOPHARYNGEAL REFLUX. Lega Natto , M.D. Nomenclature. GERD REFLUX LARYNGITIS GASTROLARYNGEAL REFLUX GASTROPHARYNGEAL REFLUX SUPRAESOPHAGEAL REFLUX LARYNGOPHARYNGEAL REFLUX. LPR.
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LegaNatto , M.D.
Epithelium and physiology
Axford SE , sharp N, Ross PE, et al. Cell biology of laryngeal epithelial defenses in health and disease: preliminary study.
Ann OtolRhinolLaryngol 110: 1099-1108, 2001
DIRECT INJURY FROM ACID OR PEPSIN
VAGALLY MEDIATED REFLEX -ACID IN LES EVOKES SYMPTOMS
Lewin JS, Gillenwater AM, Garrett JD: Characterization of Laryngopharyngeal Reflux in Patients with Premalignant or Early Carcinomas of the Larynx: CANCER FEB 2003 p.1010-1014
Qadeer MA, Colabianchi N, Vaezi MF: Is GERD a Risk Factor for Laryngeal Cancer? LARYNGOSCOPE March 2005 p.486-491
GERD likely has an etiologic role in laryngeal ca as an independent factor or co-factor in carcinogenesis