Modulating pain in CRPS with tDCS. Giridhar Gundu , M.D. PGY III Dept. of PM&R University of Kentucky 5/22/2012. Complex regional pain syndrome. CRPS is a highly painful, limb-confined condition , which arises usually after trauma.
Dept. of PM&R
University of Kentucky
Early CRPS of the right hand:
Clearly visible signs include swelling, red color and a shiny skin.
As the disease progresses some of these visible signs can partially or completely disappear while pain may persist unabated.
The IASP has proposed dividing CRPS into two types based on the presence of nerve lesion following the injury:
CRPS diagnosis is based upon clinical criteria and that there is so far no gold standard nor any objective diagnostic tool.
There is a desperate need for further research into the treatment of CRPS
The primary action of tDCS for pain reduction is direct modulation of activity in certain areas of the brain that are involved in pain processing, such as the thalamus and inhibitory corticospinal mechanisms.
Our proposed study has 2 specific aims:
4 evaluation sessions and 10 treatment sessions with each subject
Subjects must be at least 18 years of age with diagnosed CRPS following the recently updated Budapest criteria