Pharmacokinetics ADME:  A: Absorption D: Distribution M: Metabolism E: Excretion Preloader

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Principal site of drug metabolism is the liver; also kidneys, lungs, GI tract (mouth, throat, stomach, upper/lower intestines). take via mouth. . absorbed through small intestines or stomach. . . bloodstream. . liver. (first metabolized). Drug metabolism by liver enzymes ? first-pass effect. Pathway

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Pharmacokinetics ADME: A: Absorption D: Distribution M: Metabolism E: Excretion


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