Valclovir Tablets (Generic Valacyclovir Hydrochloride Tablets)

1. Valclovir Tablets (Generic Valacyclovir Hydrochloride Tablets) © Clearsky Pharmacy ( www.clearskypharmacy.biz )

2. Valclovir Tablets (Generic Valacyclovir Hydrochloride Tablets) Valclovir Tablets (Generic Valacyclovir Hydrochloride 500 mg and 1000 mg Tablets) belongs to a group of medications called antivirals. Valclovir can be used to: treat shingles (in adults), treat HSV infections of the skin and genital herpes (in adults and adolescents over 12 years old). It is also used to help prevent these infections from returning. Generic Valacyclovir tablets is also used to treat cold sores (in adults and adolescents over 12 years old), prevent infection with CMV after organ transplants (in adults and adolescents over 12 years old) and treat and prevent HSV infections of the eye that continue to come back (in adults and adolescents over 12 years old). This medicine works by killing or stopping the growth of viruses called herpes simplex (HSV), varicella zoster (VZV) and cytomegalovirus (CMV). © Clearsky Pharmacy ( www.clearskypharmacy.biz )

3. Valclovir Tablets (Generic Valacyclovir Hydrochloride Tablets) Active Ingredient The active ingredient contained in Valclovir tablets is Valacyclovir Hydrochloride. Each film-coated Valclovir tablet contains Valacyclovir Hydrochloride equivalent to 500 mg or 1000 mg of Valacyclovir respectively. © Clearsky Pharmacy ( www.clearskypharmacy.biz )

4. Valclovir Tablets (Generic Valacyclovir Hydrochloride Tablets) Chemical Structure The structure of Valacyclovir Hydrochloride is given below: © Clearsky Pharmacy ( www.clearskypharmacy.biz )

5. Valclovir Tablets (Generic Valacyclovir Hydrochloride Tablets) Valclovir Tablets (Generic Valacyclovir Hydrochloride Tablets) are manufactured by Healing Pharma India Private Limited in the strengths of 500 mg and 1000 mg. ( Website: https://www.healingpharma.in/ https://www.healingpharma.in/ ) URL: URL: https://www.clearskypharmacy.biz/generic-valacyclovir-tablets.html https://www.clearskypharmacy.biz/generic-valacyclovir-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

6. Valclovir Tablets (Generic Valacyclovir Hydrochloride Tablets) Valacyclovir Hydrochloride Tablets – Brand Names Valacyclovir Hydrochloride tablets are available under various drug trade names that include Valclovir, Centrex, Valtrex,Valcivir, Valamac and Valavir. © Clearsky Pharmacy ( www.clearskypharmacy.biz )

7. Valclovir Tablets (Generic Valacyclovir Hydrochloride Tablets) Uses of Valclovir 500 mg and 1000 mg Tablets Valclovir tablets (Generic Valacyclovir Hydrochloride tablets) is used to treat herpes virus infections, including herpes labialis (also known as cold sores), herpes zoster (also known as shingles), and herpes simplex (also known as genital herpes) in adults. It is also used to treat chickenpox and cold sores in children. In your body, Valacyclovir becomes the anti-herpes medicine, Acyclovir. Although Valacyclovir will not cure shingles or genital herpes, it does help relieve the pain and discomfort and helps the sores heal faster. URL: URL: https://www.clearskypharmacy.biz/generic-valacyclovir-tablets.html https://www.clearskypharmacy.biz/generic-valacyclovir-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

8. Valclovir Tablets (Generic Valacyclovir Hydrochloride Tablets) Valclovir Tablets Dosage The dosage of Valclovir tablets Valclovir tablets (Generic Valacyclovir Hydrochloride Tablets) is given below: Treatment of Cold Sores (Herpes Labialis) in Adults: The recommended dosage of Valclovir tablets for treatment of cold sores is 2 grams twice daily for 1 day taken 12 hours apart. Treatment should be started at the earliest symptom of a cold sore (e.g., tingling, itching, or burning). Treatment of Genital Herpes in Adults: Initial Episode: The recommended dosage of Valclovir tablets for treatment of initial genital herpes is 1 gram twice daily for 10 days. Therapy was most effective when administered within 48 hours of the onset of signs and symptoms. URL: URL: https://www.clearskypharmacy.biz/generic-valacyclovir-tablets.html https://www.clearskypharmacy.biz/generic-valacyclovir-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

9. Valclovir Tablets (Generic Valacyclovir Hydrochloride Tablets) Valclovir Tablets Dosage The dosage of Valclovir tablets Valclovir tablets (Generic Valacyclovir Hydrochloride Tablets) is given below: Treatment of Genital Herpes in Adults: Recurrent Episodes: The recommended dosage of Valclovir tablets for treatment of recurrent genital herpes is 500 mg twice daily for 3 days. Initiate treatment at the first sign or symptom of an episode. Suppressive Therapy: The recommended dosage of Valclovir tablets for chronic suppressive therapy of recurrent genital herpes is 1 gram once daily in patients with normal immune function. In patients with a history of 9 or fewer recurrences per year, an alternative dose is 500 mg once daily. In HIV-infected patients with a CD4+ cell count greater than or equal to 100 cells/mm3, the recommended dosage of Valacyclovir Hydrochloride for chronic suppressive therapy of recurrent genital herpes is 500 mg twice daily. URL: URL: https://www.clearskypharmacy.biz/generic-valacyclovir-tablets.html https://www.clearskypharmacy.biz/generic-valacyclovir-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

10. Valclovir Tablets (Generic Valacyclovir Hydrochloride Tablets) Valclovir Tablets Dosage The dosage of Valclovir tablets Valclovir tablets (Generic Valacyclovir Hydrochloride Tablets) is given below: Reduction of Transmission: The recommended dosage of Valclovir tablets for reduction of transmission of genital herpes in patients with a history of 9 or fewer recurrences per year is 500 mg once daily for the source partner. Treatment of Herpes Zoster in Adults: The recommended dosage of Valclovir tablets for treatment of herpes zoster is 1 gram 3 times daily for 7 days. Therapy should be initiated at the earliest sign or symptom of herpes zoster and is most effective when started within 48 hours of the onset of rash. URL: URL: https://www.clearskypharmacy.biz/generic-valacyclovir-tablets.html https://www.clearskypharmacy.biz/generic-valacyclovir-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

11. Valclovir Tablets (Generic Valacyclovir Hydrochloride Tablets) Valclovir Tablets Dosage The dosage of Valclovir tablets Valclovir tablets (Generic Valacyclovir Hydrochloride Tablets) is given below: Pediatric Dosing Recommendations: Cold Sores (Herpes Labialis): The recommended dosage Of Valacyclovir Hydrochloride tablets for the treatment of cold sores in pediatric patients greater than or equal to 12 years of age is 2 grams twice daily for 1 day taken 12 hours apart. Therapy should be initiated at the earliest symptom of a cold sore (e.g., tingling, itching, or burning). Chickenpox: The recommended dosage of Valacyclovir Hydrochloride tablets for treatment of chickenpox in immunocompetent pediatric patients 2 to less than 18 years of age is 20 mg/kg administered 3 times daily for 5 days. The total dose should not exceed 1 gram 3 times daily. Theatment must be initiated at the earliest sign or symptom. URL: URL: https://www.clearskypharmacy.biz/generic-valacyclovir-tablets.html https://www.clearskypharmacy.biz/generic-valacyclovir-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

12. Valclovir Tablets (Generic Valacyclovir Hydrochloride Tablets) Valclovir Tablets Contraindications Valclovir tablets are contraindicated in patients with a hypersensitivity to Valacyclovir Hydrochloride (e.g., anaphylaxis), Acyclovir, or any other component of this medication. URL: URL: https://www.clearskypharmacy.biz/generic-valacyclovir-tablets.html https://www.clearskypharmacy.biz/generic-valacyclovir-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

13. Valclovir Tablets (Generic Valacyclovir Hydrochloride Tablets) Storage Instructions Valclovir tablets (Generic Valacyclovir Hydrochloride tablets) have to be stored at controlled room temperature i.e. from 20°C to 25°C (68°F to 77°F) with excursions permitted between 15° to 30°C (59° to 86°F). Keep this as well as all other medicines away from children and pets. URL: URL: https://www.clearskypharmacy.biz/generic-valacyclovir-tablets.html https://www.clearskypharmacy.biz/generic-valacyclovir-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

14. Valclovir Tablets (Generic Valacyclovir Hydrochloride Tablets) Warnings Thrombotic thrombocytopenic purpura/hemolytic uremic syndrome (TTP/HUS): Has occurred in patients with advanced HIV disease and in allogenic bone marrow transplant and renal transplant patients receiving 8 grams per day of Generic Valacyclovir in clinical trials. Discontinue treatment if clinical symptoms and laboratory findings consistent with TTP/HUS occur. Acute renal failure: May occur in elderly patients (with or without reduced renal function), patients with underlying renal disease who receive higher than recommended doses of Generic Valacyclovir for their level of renal function, patients who receive concomitant nephrotoxic drugs, or inadequately hydrated patients. Use with caution in elderly patients and reduce dosage in patients with renal impairment. © Clearsky Pharmacy ( www.clearskypharmacy.biz )

15. Valclovir Tablets (Generic Valacyclovir Hydrochloride Tablets) Warnings Central nervous system adverse reactions (e.g., agitation, hallucinations, confusion, and encephalopathy): May occur in elderly patients (with or without reduced renal function) and in patients with underlying renal disease who receive higher than recommended doses of Generic Valacyclovir for their level of renal function. Use with caution in elderly patients and reduce dosage in patients with renal impairment. URL: URL: https://www.clearskypharmacy.biz/generic-valacyclovir-tablets.html https://www.clearskypharmacy.biz/generic-valacyclovir-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

16. Valclovir Tablets (Generic Valacyclovir Hydrochloride Tablets) Valclovir Tablets Side Effects The most common Valacyclovir Hydrochloride(Valclovir tablets) side effects reported in at least 1 indication by greater than 10% of adult subjects treated with Valacyclovir Hydrochloride and observed more frequently with Valacyclovir Hydrochloride compared with placebo are headache, nausea, and abdominal pain. The only adverse reaction reported in greater than 10% of pediatric subjects aged less than 18 years was headache. The serious side effects include: Thrombotic Thrombocytopenic Purpura/Hemolytic Uremic Syndrome, Acute Renal Failure and Central Nervous System Effects. URL: URL: https://www.clearskypharmacy.biz/generic-valacyclovir-tablets.html https://www.clearskypharmacy.biz/generic-valacyclovir-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

17. Valclovir Tablets (Generic Valacyclovir Hydrochloride Tablets) Overdose Caution should be exercised to prevent inadvertent Valacyclovir Hydrochloride(Valclovir tablets) overdose. Precipitation of Acyclovir in renal tubules may occur when the solubility (2.5 mg/mL) is exceeded in the intratubular fluid. In the event of acute renal failure and anuria, the patient may benefit from hemodialysis until renal function is restored. URL: URL: https://www.clearskypharmacy.biz/generic-valacyclovir-tablets.html https://www.clearskypharmacy.biz/generic-valacyclovir-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

18. Valclovir Tablets (Generic Valacyclovir Hydrochloride Tablets) Valclovir Tablets During Pregnancy Valacyclovir Hydrochloride (Valclovir tablets) has been classified by the US FDA as Pregnancy Category B. There are no adequate and well-controlled studies of Valacyclovir tablets or Acyclovir in pregnant women. Animal reproduction studies performed at oral doses that provided up to 10 and 7 times the human plasma levels during the period of major organogenesis in rats and rabbits, respectively, revealed no evidence of teratogenicity. Based on pregnancy registry data the overall rate of birth defects in infants exposed to Acyclovir in- utero appears similar to the rate for infants in the general population. Valclovir tablets must be used during pregnancy only if the potential benefit justifies the potential risk to the foetus. URL: URL: https://www.clearskypharmacy.biz/generic-valacyclovir-tablets.html https://www.clearskypharmacy.biz/generic-valacyclovir-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

19. Valclovir Tablets (Generic Valacyclovir Hydrochloride Tablets) For more details on Valclovir Tablets click here Valclovir Tablets click here Valclovir Tablets (Generic Valacyclovir Hydrochloride Tablets) by Healing Pharma India Private Limited. URL: URL: https://www.clearskypharmacy.biz/generic-valacyclovir-tablets.html https://www.clearskypharmacy.biz/generic-valacyclovir-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )