Thyronorm Tablets (Generic Levothyroxine Sodium Tablets)

1. Thyronorm Tablets (Generic Levothyroxine Sodium Tablets) © Clearsky Pharmacy ( www.clearskypharmacy.biz )

2. Thyronorm Tablets (Generic Levothyroxine Sodium Tablets) Thyronorm (Generic Levothyroxine Sodium Tablets) is used as a replacement therapy in primary (thyroidal), secondary (pituitary), and tertiary (hypothalamic) congenital or acquired hypothyroidism. Symptoms of hypothyroidism include tiredness, muscle weakness, and cramps, feeling the cold, a slow heart rate, dry and flaky skin, hair loss, a deep husky voice and weight gain. Levothyroxine sodium tablets are also indicated as an adjunct to surgery and radioiodine therapy in the management of thyrotropin-dependent well-differentiated thyroid cancer. © Clearsky Pharmacy ( www.clearskypharmacy.biz )

3. Thyronorm Tablets (Generic Levothyroxine Sodium Tablets) Active Ingredient The active ingredient contained in Thyronorm tablets is Thyroxine Sodium (Levothyroxine Sodium). Each uncoated Thyronorm tablet contains 12.5 mcg, 25 mcg, 50 mcg, 62.5 mcg, 75 mcg, 88 mcg, 100 mcg, 112 mcg, 125 mcg or 150 mcg of Levothyroxine Sodium. © Clearsky Pharmacy ( www.clearskypharmacy.biz )

4. Thyronorm Tablets (Generic Levothyroxine Sodium Tablets) Chemical Structure The structure of Levothyroxine Sodium is given below: © Clearsky Pharmacy ( www.clearskypharmacy.biz )

5. Thyronorm Tablets (Generic Levothyroxine Sodium Tablets) Thyronorm Tablets are manufactured by Abbott India Limited in the strengths of 12.5 mcg, 25 mcg, 50 mcg, 62.5 mcg, 75 mcg, 88 mcg, 100 mcg, 112 mcg, 125 mcg and 150 mcg. ( Website: https://www.abbott.co.in/ https://www.abbott.co.in/ ) URL: URL: https://www.clearskypharmacy.biz/synthroid-thyronorm-by-abbott.html https://www.clearskypharmacy.biz/synthroid-thyronorm-by-abbott.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

6. Thyronorm Tablets (Generic Levothyroxine Sodium Tablets) Levothyroxine Sodium Tablets – Brand Names Levothyroxine Sodium tablets are available as Thyronorm, Eltroxin, Thyrax, Euthyrox, Levaxin, L-thyroxine, Thyrax, Duotab, Thyrox, Eutirox, Tirosint and Levoxyl. © Clearsky Pharmacy ( www.clearskypharmacy.biz )

7. Thyronorm Tablets (Generic Levothyroxine Sodium Tablets) Uses of Thyronorm Tablets Levothyroxine Sodium (Thyronorm tablets) is used to treat an underactive thyroid (hypothyroidism), a condition where the thyroid gland does not produce enough thyroid hormone. Levothyroxine is also used to help decrease the size of enlarged thyroid glands (also called a goiter) and to treat thyroid cancer. It replaces or provides more thyroid hormone, which is normally produced by the thyroid gland. Low thyroid hormone levels can occur naturally or when the thyroid gland is injured by radiation/medications or removed by surgery. Having enough thyroid hormone is important for maintaining normal mental and physical activity. In children, having enough thyroid hormone is important for normal mental and physical development. This medication should not be used to treat infertility unless it is caused by low thyroid hormone levels. URL: URL: https://www.clearskypharmacy.biz/synthroid-thyronorm-by-abbott.html https://www.clearskypharmacy.biz/synthroid-thyronorm-by-abbott.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

8. Thyronorm Tablets (Generic Levothyroxine Sodium Tablets) Thyronorm Tablets Dosage The dosage of Thyronorm tablets Thyronorm tablets (Levothyroxine Sodium) is given below: Thyronorm (Generic Levothyroxine Sodium Tablets) should be taken on an empty stomach, preferably before breakfast. Thyronorm should be administered at least 4 hours apart from drugs that are known to interfere with its absorption. The recommended initial Thyronorm dosage in adult patients is 50 to 100 micrograms daily and adjust at 4 to 6 week intervals by 50 micrograms until normal metabolism is steadily maintained. URL: URL: https://www.clearskypharmacy.biz/synthroid-thyronorm-by-abbott.html https://www.clearskypharmacy.biz/synthroid-thyronorm-by-abbott.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

9. Thyronorm Tablets (Generic Levothyroxine Sodium Tablets) Thyronorm Tablets Dosage The dosage of Thyronorm tablets Thyronorm tablets (Levothyroxine Sodium) is given below: For patients over 50 years, initially, it is not advisable to exceed 50 micrograms daily. In this condition, the daily dose may be increased by 50 micrograms at intervals of every 3 to 4 weeks, until stable thyroxine levels are attained. The final daily dose may be up to 50 to 200 micrograms. Take your Generic Levothyroxine tablet with a full glass of water. URL: URL: https://www.clearskypharmacy.biz/synthroid-thyronorm-by-abbott.html https://www.clearskypharmacy.biz/synthroid-thyronorm-by-abbott.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

10. Thyronorm Tablets (Generic Levothyroxine Sodium Tablets) Contraindications Thyronorm is contraindicated in patients with a hypersensitivity to Levothyroxine Sodium or any other component of this medication. Levothyroxine Sodium Tablets are also contraindicated in patients with untreated subclinical (suppressed serum TSH with normal T3 and T4 levels) or overt thyrotoxicosis of any etiology. Levothyroxine sodium is contraindicated in patients with uncorrected adrenal insufficiency. URL: URL: https://www.clearskypharmacy.biz/synthroid-thyronorm-by-abbott.html https://www.clearskypharmacy.biz/synthroid-thyronorm-by-abbott.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

11. Thyronorm Tablets (Generic Levothyroxine Sodium Tablets) Storage Instructions Thyronorm Tablets (Generic Levothyroxine Sodium Tablets) have to be stored at controlled room temperature i.e. from 20°C to 25°C (68°F to 77°F) with excursions permitted between 15° to 30°C (59° to 86°F). Keep this as well as all other medicines away from children and pets. URL: URL: https://www.clearskypharmacy.biz/synthroid-thyronorm-by-abbott.html https://www.clearskypharmacy.biz/synthroid-thyronorm-by-abbott.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

12. Thyronorm Tablets (Generic Levothyroxine Sodium Tablets) Warnings Cardiac adverse reactions in the elderly and in patients with underlying cardiovascular disease: Initiate Thyronorm at less than the full replacement dose because of the increased risk of cardiac adverse reactions, including atrial fibrillation. Myxedema coma: Do not use oral thyroid hormone drug products to treat myxedema coma. Acute adrenal crisis in patients with concomitant adrenal insufficiency: Treat with replacement glucocorticoids prior to initiation of Thyronorm treatment. Prevention of hyperthyroidism or incomplete treatment of hypothyroidism: Proper dose titration and careful monitoring is critical to prevent the persistence of hypothyroidism or the development of hyperthyroidism. URL: URL: https://www.clearskypharmacy.biz/synthroid-thyronorm-by-abbott.html https://www.clearskypharmacy.biz/synthroid-thyronorm-by-abbott.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

13. Thyronorm Tablets (Generic Levothyroxine Sodium Tablets) Warnings Worsening of diabetic control: Therapy in patients with diabetes mellitus may worsen glycemic control and result in increased antidiabetic agent or insulin requirements. Carefully monitor glycemic control after starting, changing, or discontinuing thyroid hormone therapy. Decreased bone mineral density associated with thyroid hormone over-replacement: Over-replacement can increase bone resorption and decrease bone mineral density. Give the lowest effective dose. URL: URL: https://www.clearskypharmacy.biz/synthroid-thyronorm-by-abbott.html https://www.clearskypharmacy.biz/synthroid-thyronorm-by-abbott.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

14. Thyronorm Tablets (Generic Levothyroxine Sodium Tablets) Side Effects Side effects associated with Levothyroxine Sodium (Thyronorm Tablets) therapy are primarily those of hyperthyroidism due to therapeutic overdosage: arrhythmias, myocardial infarction, dyspnea, muscle spasm, headache, nervousness, irritability, insomnia, tremors, muscle weakness, increased appetite, weight loss, diarrhea, heat intolerance, menstrual irregularities, and skin rash. URL: URL: https://www.clearskypharmacy.biz/synthroid-thyronorm-by-abbott.html https://www.clearskypharmacy.biz/synthroid-thyronorm-by-abbott.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

15. Thyronorm Tablets (Generic Levothyroxine Sodium Tablets) Side Effects The following Thyronorm side effects are indicative of excessive dosage and usually disappear on reduction of dosage or withdrawal of treatment for a few days. General: fatigue, increased appetite, weight loss, heat intolerance, fever, excessive sweating Central nervous system: headache, hyperactivity, nervousness, anxiety, irritability, emotional lability, insomnia Musculoskeletal: tremors, muscle weakness, muscle spasm Cardiovascular: palpitations, tachycardia, arrhythmias, increased pulse and blood pressure, heart failure, angina, myocardial infarction, cardiac arrest Respiratory: dyspnea Gastrointestinal: diarrhea, vomiting, abdominal cramps, elevations in liver function tests Dermatologic: hair loss, flushing, rash Endocrine: decreased bone mineral density Reproductive: menstrual irregularities, impaired fertility Seizures have been reported rarely with the institution of levothyroxine therapy. URL: URL: https://www.clearskypharmacy.biz/synthroid-thyronorm-by-abbott.html https://www.clearskypharmacy.biz/synthroid-thyronorm-by-abbott.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

16. Thyronorm Tablets (Generic Levothyroxine Sodium Tablets) Overdose The signs and symptoms of overdosage are those of hyperthyroidism. In addition, confusion and disorientation may occur. Cerebral embolism, shock, coma, and death have been reported. Seizures occurred in a 3-year-old child ingesting 3.6 mg of Levothyroxine Sodium. Symptoms may not necessarily be evident or may not appear until several days after ingestion of Levothyroxine Sodium. URL: URL: https://www.clearskypharmacy.biz/synthroid-thyronorm-by-abbott.html https://www.clearskypharmacy.biz/synthroid-thyronorm-by-abbott.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

17. Thyronorm Tablets (Generic Levothyroxine Sodium Tablets) Overdose Reduce the Thyronorm (Generic Levothyroxine Sodium Tablets) dose or discontinue temporarily if signs or symptoms of overdosage occur. Initiate appropriate supportive treatment as dictated by the patient’s medical status. URL: URL: https://www.clearskypharmacy.biz/synthroid-thyronorm-by-abbott.html https://www.clearskypharmacy.biz/synthroid-thyronorm-by-abbott.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

18. Thyronorm Tablets (Generic Levothyroxine Sodium Tablets) Thyronorm Tablets During Pregnancy Thyronorm (Levothyroxine Sodium tablets) has been classified by the US FDA as Pregnancy Category A. Studies in women taking Levothyroxine Sodium (Thyronorm Tablets) during pregnancy have not shown an increased risk of congenital abnormalities. Experience with Levothyroxine Sodium (Thyronorm Tablets) use in pregnant women, including data from post-marketing studies, have not reported increased rates of major birth defects or miscarriages. There are risks to the mother and fetus associated with untreated hypothyroidism in pregnancy. URL: URL: https://www.clearskypharmacy.biz/synthroid-thyronorm-by-abbott.html https://www.clearskypharmacy.biz/synthroid-thyronorm-by-abbott.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

19. Thyronorm Tablets (Generic Levothyroxine Sodium Tablets) Thyronorm Tablets During Pregnancy Thyronorm (Levothyroxine Sodium tablets) has been classified by the US FDA as Pregnancy Category A. Since TSH levels may increase during pregnancy, TSH should be monitored and Levothyroxine Sodium (Thyronorm Tablets) dosage adjusted during pregnancy. There are no animal studies conducted with Levothyroxine during pregnancy. Thyronorm should not be discontinued during pregnancy and hypothyroidism diagnosed during pregnancy should be promptly treated. URL: URL: https://www.clearskypharmacy.biz/synthroid-thyronorm-by-abbott.html https://www.clearskypharmacy.biz/synthroid-thyronorm-by-abbott.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

20. Thyronorm Tablets (Generic Levothyroxine Sodium Tablets) For more details on For more details on Thyronorm Tablets click here Thyronorm Tablets click here Thyronorm tablets (Generic Levothyroxine Sodium tablets) by Abbott India Limited. URL: URL: https://www.clearskypharmacy.biz/synthroid-thyronorm-by-abbott.html https://www.clearskypharmacy.biz/synthroid-thyronorm-by-abbott.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )