Calpol Tablets (Generic Acetaminophen Tablets)

1. Calpol Tablets (Generic Acetaminophen Tablets) © Clearsky Pharmacy ( www.clearskypharmacy.biz )

2. Calpol Tablets (Generic Acetaminophen Tablets) Calpol Tablets (Generic Acetaminophen Tablets) is used for the quick and effective temporary relief of pain and discomfort associated with Headache, Muscular aches, Period pain, Arthritis / Osteoarthritis, Toothache, Migraine, Colds and flu, Tension headache, Sinus pain/headache and Backache. Also indicated for the symptomatic reduction of fever due to the common cold, flu and other viral or bacterial infections. © Clearsky Pharmacy ( www.clearskypharmacy.biz )

3. Calpol Tablets (Generic Acetaminophen Tablets) Active Ingredient The active ingredient contained in in Calpol tablets is Paracetamol, also known as Acetaminophen or APAP. Each Calpol tablet contains 500 mg or 650 mg of Acetaminophen respectively. © Clearsky Pharmacy ( www.clearskypharmacy.biz )

4. Calpol Tablets (Generic Acetaminophen Tablets) Chemical Structure The structure of Paracetamol (Acetaminophen) is given below: © Clearsky Pharmacy ( www.clearskypharmacy.biz )

5. Calpol Tablets (Generic Acetaminophen Tablets) Calpol tablets , manufactured by GlaxoSmithKline Pharmaceuticals Limited, India are available as tablets in the strengths of 500 mg and 650 mg. (Website: https://india-pharma.gsk.com/ ) URL: https://www.clearskypharmacy.biz/paracetamol-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

6. Calpol Tablets (Generic Acetaminophen Tablets) Acetaminophen (Paracetamol) Tablets – Brand Names Acetaminophen (Paracetamol) tablets are available under various drug trade names that include Panadol, Calpol, Crocin, Cofamol, Ultragin, Algina, Dolo, Almol Forte, Biocetamol-500, Biocetamol-650, Febrex, Febrinil, Nicetamol, Parafizz, Temfix. © Clearsky Pharmacy ( www.clearskypharmacy.biz )

7. Calpol Tablets (Generic Acetaminophen Tablets) Uses of Calpol Tablets Calpol Tablets (Generic Acetaminophen Tablets) is a mild analgesic and antipyretic, and is recommended for the treatment of most painful and febrile conditions, for example, headache including migraine, toothache, neuralgia, colds and influenza, sore throat, backache, rheumatic pain and dysmenorrhoea. Acetaminophen (Paracetamol) is thought to work by blocking chemical messengers in the brain that let us know when we're in pain and by affecting the chemical messengers that regulate our body temperature. The evidence suggests that paracetamol inhibits the production of prostaglandins, which are made by the body to deal with illness and injury. It's also thought to act on the serotonergic, opioid, nitric oxide and cannabinoid pathways. URL: https://www.clearskypharmacy.biz/paracetamol-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

8. Calpol Tablets (Generic Acetaminophen Tablets) Calpol Tablets Dosage The dosage of Calpol tablets (Generic Acetaminophen Tablets) is given below: The recommended dosage of Calpol 500 mg tablets for Adults and Children 12 years and over: Take 1 tablet every 3 to 4 hours or 2 tablets every 6 hours while symptoms last. Do not take more than 6 tablets (3,000 mg of Acetaminophen in 24 hours) in any 24 hour period. The recommended dosage of Calpol 650 mg tablets for Adults (above 18 years old): Take 2 tablets every 8 hours with water. Swallow whole; do not crush, chew, split or dissolve. Do not take more than 6 tablets in any 24 hours period. Do not use for more than 10 days unless directed by a doctor. Patients under 18 years of age: Ask a doctor URL: https://www.clearskypharmacy.biz/paracetamol-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

9. Calpol Tablets (Generic Acetaminophen Tablets) Contraindications Calpol tablets are contraindicated in patients with a hypersensitivity to Paracetamol (also known as Acetaminophen or APAP) or any other component of this medication. Allergic reactions (primarily skin rash) or reports of hypersensitivity secondary to Acetaminophen are rare and generally are controlled by discontinuation of the drug and, when necessary, symptomatic treatment. Do not use with any other product containing Acetaminophen. You should not use this medication if you have severe liver disease. URL: https://www.clearskypharmacy.biz/paracetamol-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

10. Calpol Tablets (Generic Acetaminophen Tablets) Storage Instructions Calpol Tablets (Generic Acetaminophen Tablets) have to be stored at controlled room temperature i.e. from 20°C to 25°C (68°F to 77°F) with excursions permitted between 15° to 30°C (59° to 86°F). Keep this as well as all other medicines away from children and pets. URL: https://www.clearskypharmacy.biz/paracetamol-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

11. Calpol Tablets (Generic Acetaminophen Tablets) Warnings Calpol tablets contain Acetaminophen. The maximum daily dose of this product is 6 tablets (3,000 mg) in any 24 hour period. Severe liver damage could occur if you take more than 4,000 mg of acetaminophen in 24 hours. Do not administer this medicine with other drugs containing Acetaminophen (Paracetamol). Do not consume 3 or more alcoholic drinks every day while using this product. You should not use this medicine if you have severe liver disease. The hazards of overdose are greater in those with non-cirrhotic alcoholic liver disease. Do not give this medicine to a child younger than 12 years old without the advice of a doctor. URL: https://www.clearskypharmacy.biz/paracetamol-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

12. Calpol Tablets (Generic Acetaminophen Tablets) Warnings Where analgesics are used long-term (greater than 3 months) with administration every two days or more frequently, headache may develop or worsen. Headache induced by overuse of analgesics (MOH medication- overuse headache) should not be treated by dose increase. In such cases, the use of analgesics should be discontinued in consultation with the doctor. Immediate medical advice should be sought in the event of an overdose, even if you feel well, because of the risk of delayed, serious liver damage. URL: https://www.clearskypharmacy.biz/paracetamol-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

13. Calpol Tablets (Generic Acetaminophen Tablets) Side Effects Side effects of Calpol Tablets (Generic Acetaminophen tablets) are rare and usually mild, although haematological reactions have been reported. Skin rashes and other hypersensitivity reactions occur occasionally. The most common side effects in patients treated with Acetaminophen were nausea, vomiting, headache, and insomnia in adult patients and nausea, vomiting, constipation, pruritus, agitation, and atelectasis in pediatric patients. URL: https://www.clearskypharmacy.biz/paracetamol-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

14. Calpol Tablets (Generic Acetaminophen Tablets) Overdose There is a risk of poisoning, particularly in elderly subjects, in young children, in patients with liver disease, in cases of chronic alcoholism, in patients with chronic malnutrition and in patients receiving enzyme inducers. Poisoning may be fatal in these cases. Acute overdose with Acetaminophen (Paracetamol) may also lead to acute renal tubular necrosis. In acute acetaminophen overdosage, dose -dependent, potentially fatal hepatic necrosis is the most serious adverse effect. Renal tubular necrosis, hypoglycemic coma, and thrombocytopenia may also occur. Early symptoms following a potentially hepatotoxic overdose may include: nausea, vomiting, diaphoresis, and general malaise. URL: https://www.clearskypharmacy.biz/paracetamol-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

15. Calpol Tablets (Generic Acetaminophen Tablets) Overdose Clinical and laboratory evidence of hepatic toxicity may not be apparent until 48 to 72 hours post-ingestion. If an Acetaminophen overdose is suspected, obtain a serum Acetaminophen assay as soon as possible, but no sooner than 4 hours following oral ingestion. Obtain liver function studies initially and repeat at 24-hour intervals. Administer the antidote N-acetylcysteine (NAC) as soon as possible. URL: https://www.clearskypharmacy.biz/paracetamol-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

16. Calpol Tablets (Generic Acetaminophen Tablets) Calpol Tablets During Pregnancy Acetaminophen (Calpol tablets) has been classified by the US FDA as Pregnancy Category C. Use of this medicine during pregnancy should be avoided unless advised by a doctor. This includes maternal use during labor because of the potential of respiratory depression in the neonate. The safety of Acetaminophen (Paracetamol) during pregnancy has not been established relative to possible adverse effects on foetal development. Do not use this medicine without the advice of your doctor if you are pregnant. URL: https://www.clearskypharmacy.biz/paracetamol-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

17. Calpol Tablets (Generic Acetaminophen Tablets) For more details on Calpol Tablets click here Calpol Tablets (Generic Acetaminophen Tablets) by GlaxoSmithKline Pharmaceuticals Limited, India. URL: https://www.clearskypharmacy.biz/paracetamol-tablets.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )