Buspin Tablets (Generic Buspirone Hydrochloride Tablets)

1. Buspin Tablets (Generic Buspirone Hydrochloride Tablets) © Clearsky Pharmacy ( www.clearskypharmacy.biz )

2. Buspin Tablets (Generic Buspirone Hydrochloride Tablets) Buspin (Generic Buspirone Hydrochloride tablets) is indicated for short-term use in cases of anxiety and to relieve the symptoms of anxiety with or without accompanying depression. Buspirone is used to treat symptoms of anxiety, such as fear, tension, irritability, dizziness, pounding heartbeat, and other physical symptoms. Buspirone is thought to work by decreasing the amount and actions of a chemical known as serotonin in certain parts of the brain. The efficacy of Buspirone Hydrochloride tablets has been demonstrated in controlled clinical trials of outpatients whose diagnosis roughly corresponds to Generalized Anxiety Disorder (GAD). © Clearsky Pharmacy ( www.clearskypharmacy.biz )

3. Buspin Tablets (Generic Buspirone Hydrochloride Tablets) Active Ingredient The active ingredient present in Buspin tablets is Buspirone Hydrochloride. Each tablet of Buspin contains either 5 mg or 10 mg of Buspirone Hydrochloride. © Clearsky Pharmacy ( www.clearskypharmacy.biz )

4. Buspin Tablets (Generic Buspirone Hydrochloride Tablets) Chemical Structure The structure of Buspirone Hydrochloride is given below: © Clearsky Pharmacy ( www.clearskypharmacy.biz )

5. Buspin Tablets (Generic Buspirone Hydrochloride Tablets) Buspin tablets (Generic Buspirone Hydrochloride Tablets) are manufactured by Intas Pharmaceuticals Limited, India in the strengths of 5 mg and 10 mg. (Website: https://www.intaspharma.com/ https://www.intaspharma.com/ ) URL: URL: https://www.clearskypharmacy.biz/generic-buspar-buspin-by-intas.html https://www.clearskypharmacy.biz/generic-buspar-buspin-by-intas.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

6. Buspin Tablets (Generic Buspirone Hydrochloride Tablets) Buspirone Hydrochloride Tablets – Brand Names Buspirone Hydrochloride tablets are available under various drug brand names that include Buspar , Buspar Dividose, Buspin from Intas, Vanspar, Buscalm from Wockhardt (Merind) , Buson from Kramer , Buspidac from Zydus (Alidac) , Buspitor (Torcium), Supiron-B from Psycorem, Biziron (Consern) and Tamspar (Sun Pharma). © Clearsky Pharmacy ( www.clearskypharmacy.biz )

7. Buspin Tablets (Generic Buspirone Hydrochloride Tablets) Uses of Buspin 5 mg and 10 mg Tablets Buspin tablets (Generic Buspirone Hydrochloride Tablets) are used to treat certain anxiety disorders or to relieve the symptoms of anxiety. However, buspirone usually is not used for anxiety or tension caused by the stress of everyday life. It is not known exactly how Buspirone works to relieve the symptoms of anxiety. Buspirone is thought to work by decreasing the amount and actions of a chemical known as serotonin in certain parts of the brain. URL: URL: https://www.clearskypharmacy.biz/generic-buspar-buspin-by-intas.html https://www.clearskypharmacy.biz/generic-buspar-buspin-by-intas.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

8. Buspin Tablets (Generic Buspirone Hydrochloride Tablets) Buspin Tablets Dosage The recommended starting dose of Buspin tablets Buspirone Hydrochloride tablets) is 5 mg given three times daily. This may be titrated according to the needs of the patient and the daily dose increased by 5 mg increments every two or three days depending upon the therapeutic response to a maximum daily dose of 60 mg. After dosage titration the usual daily dose will be 20 to 30 mg per day in divided doses. Food increases the bioavailability of buspirone. Buspin tablets (Buspirone Hydrochloride tablets) should be taken at the same time each day and consistently with or without food. Buspin tablets (Generic URL: URL: https://www.clearskypharmacy.biz/generic-buspar-buspin-by-intas.html https://www.clearskypharmacy.biz/generic-buspar-buspin-by-intas.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

9. Buspin Tablets (Generic Buspirone Hydrochloride Tablets) Contraindications Buspin tablets are contraindicated in persons with a hypersensitivity (allergy) to Buspirone Hydrochloride or any of the other ingredients of this medicine. Buspin is contraindicated in patients with Acute angle, closure glaucoma, Myasthenia gravis, Severe hepatic insufficiency, Severe renal insufficiency (eGFR less than 20 ml/min/1.73m2) and epilepsy. This medicine is also contraindicated in cases of acute intoxication with alcohol, hypnotics, analgesics, or antipsychotic medicines. URL: URL: https://www.clearskypharmacy.biz/generic-buspar-buspin-by-intas.html https://www.clearskypharmacy.biz/generic-buspar-buspin-by-intas.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

10. Buspin Tablets (Generic Buspirone Hydrochloride Tablets) Storage Instructions Buspin Tablets (Generic Buspirone Hydrochloride Tablets) have to be stored at controlled room temperature i.e. from 20°C to 25°C (68°F to 77°F) with excursions permitted between 15° to 30°C (59° to 86°F). Keep this as well as all other medicines away from children and pets. URL: URL: https://www.clearskypharmacy.biz/generic-buspar-buspin-by-intas.html https://www.clearskypharmacy.biz/generic-buspar-buspin-by-intas.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

11. Buspin Tablets (Generic Buspirone Hydrochloride Tablets) Warnings The administration of Buspirone Hydrochloride tablets to a patient taking a monoamine oxidase inhibitor (MAOI) may pose a hazard. There have been reports of the occurrence of elevated blood pressure when Buspirone Hydrochloride has been added to a regimen including an MAOI. The development of a potentially life-threatening serotonin syndrome has been reported with SNRIs, SSRIs, and other serotonergic drugs, including Buspirone Hydrochloride (Buspin Tablets), alone but particularly with concomitant use of other serotonergic drugs (including triptans), with drugs that impair metabolism of serotonin (in particular, MAOIs, including reversible MAOIs such as linezolid and intravenous methylene blue), or with antipsychotics or other dopamine antagonists. © Clearsky Pharmacy ( www.clearskypharmacy.biz )

12. Buspin Tablets (Generic Buspirone Hydrochloride Tablets) Warnings Renal Impairment: Buspirone Hydrochloride (Buspin Tablets) should be used cautiously in patients with renal disease. Since Buspirone is excreted by the kidneys the dose should be reduced in patients with renal impairment but administration of Buspirone to patients with severe renal impairment cannot be recommended. Hepatic Impairment: Buspirone should be used cautiously, at reduced doses, in patients with impaired hepatic function or may be contraindicated (see Contraindications). Buspirone clearance is reduced in patients with hepatic cirrhosis. URL: URL: https://www.clearskypharmacy.biz/generic-buspar-buspin-by-intas.html https://www.clearskypharmacy.biz/generic-buspar-buspin-by-intas.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

13. Buspin Tablets (Generic Buspirone Hydrochloride Tablets) Warnings Central Dopaminergic Receptor Binding:The possibility of acute and chronic changes in dopamine mediated neurological function (e.g. dystonia, pseudo-Parkinsonism, akathisia and tardive dyskinesia) should be considered since animal studies have shown that Buspirone Hydrochloride (Buspin Tablets) can bind to central dopamine receptors. Paediatric population: Buspirone should not be used in children and adolescents under 18 years of age as the safety and efficacy have not been established in this age group. URL: URL: https://www.clearskypharmacy.biz/generic-buspar-buspin-by-intas.html https://www.clearskypharmacy.biz/generic-buspar-buspin-by-intas.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

14. Buspin Tablets (Generic Buspirone Hydrochloride Tablets) Side Effects Side effects that occurred at a frequency of 1% or more among Buspirone Hydrochloride (Buspin Tablets) patients who participated in 4 week, controlled trials comparing Buspirone Hydrochloride tablets (Buspin) with placebo. Cardiovascular: Tachycardia/Palpitations CNS: Dizziness, Drowsiness, Nervousness, Insomnia, Lightheadedness, Decreased concentration, Excitement, Anger/Hostility, Confusion, Depression EENT: Blurred vision Gastrointestinal: Nausea, Dry mouth, Abdominal/gastric distress, Diarrhea, Constipation, Vomiting Musculoskeletal: Musculoskeletal aches/pains Neurological: Numbness, Paresthesia, Incoordination, Tremor Skin: Skin rash Miscellaneous: Headache, Fatigue, Weakness, Sweating/Clamminess URL: URL: https://www.clearskypharmacy.biz/generic-buspar-buspin-by-intas.html https://www.clearskypharmacy.biz/generic-buspar-buspin-by-intas.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

15. Buspin Tablets (Generic Buspirone Hydrochloride Tablets) Overdose In clinical pharmacology trials, doses as high as 375 mg/day were administered to healthy male volunteers. As this dose was approached, the following symptoms were observed: nausea, vomiting, dizziness, drowsiness, miosis, and gastric distress. A few cases of overdosage have been reported, with complete recovery as the usual outcome. No deaths have been reported following overdosage with Buspirone Hydrochloride tablets (Buspin Tablets) alone. URL: URL: https://www.clearskypharmacy.biz/generic-buspar-buspin-by-intas.html https://www.clearskypharmacy.biz/generic-buspar-buspin-by-intas.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

16. Buspin Tablets (Generic Buspirone Hydrochloride Tablets) Overdose General symptomatic and supportive measures should be used along with immediate gastric lavage. Respiration, pulse, and blood pressure should be monitored as in all cases of drug overdosage. No specific antidote is known to Buspirone Hydrochloride (Buspin Tablets), and dialyzability of Buspirone has not been determined. URL: URL: https://www.clearskypharmacy.biz/generic-buspar-buspin-by-intas.html https://www.clearskypharmacy.biz/generic-buspar-buspin-by-intas.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

17. Buspin Tablets (Generic Buspirone Hydrochloride Tablets) Buspin Tablets During Pregnancy Buspirone Hydrochloride (Buspin Tablets) has been classified by the US FDA as Pregnancy Category B. No fertility impairment or fetal damage was observed in reproduction studies performed in rats and rabbits at buspirone doses of approximately 30 times the maximum recommended human dose. In humans, however, adequate and well-controlled studies during pregnancy have not been performed. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed. URL: URL: https://www.clearskypharmacy.biz/generic-buspar-buspin-by-intas.html https://www.clearskypharmacy.biz/generic-buspar-buspin-by-intas.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

18. Buspin Tablets (Generic Buspirone Hydrochloride Tablets) For more details on Buspin Tablets click here Buspin Tablets click here Buspin (Generic Buspirone Hydrochloride tablets) by Intas Pharmaceuticals Limited, India. URL: URL: https://www.clearskypharmacy.biz/generic-buspar-buspin-by-intas.html https://www.clearskypharmacy.biz/generic-buspar-buspin-by-intas.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )