Bupron SR Tablets (Generic Bupropion Hydrochloride SR Tablets)

1. Bupron SR Tablets (Generic Bupropion Hydrochloride SR Tablets) © Clearsky Pharmacy ( www.clearskypharmacy.biz )

2. Bupron SR Tablets (Generic Bupropion Hydrochloride SR Tablets) Bupron SR (Generic Bupropion Hydrochloride SR tablets) is used as an aid to smoking cessation in combination with a stop-smoking program (e.g., support group, counseling) to help nicotine-dependent patients quit smoking. Bupropion can decrease your nicotine withdrawal symptoms (e.g., irritability, anxiety, restlessness) and your urge to smoke. Quitting smoking decreases your risk of heart and lung disease, as well as cancer. Bupron SR belongs to a class of medications known as antidepressants. It is not known exactly how Bupropion works to reduce smoking urges. It may work by restoring the balance of certain natural chemicals (neurotransmitters) in the brain. © Clearsky Pharmacy ( www.clearskypharmacy.biz )

3. Bupron SR Tablets (Generic Bupropion Hydrochloride SR Tablets) Active Ingredient The active ingredient present in Bupron SR tablets is Bupropion Hydrochloride. Each film coated extended release Bupron SR tablet contains 150 mg of Bupropion Hydrochloride. © Clearsky Pharmacy ( www.clearskypharmacy.biz )

4. Bupron SR Tablets (Generic Bupropion Hydrochloride SR Tablets) Chemical Structure The structure of Bupropion Hydrochloride is given below: © Clearsky Pharmacy ( www.clearskypharmacy.biz )

5. Bupron SR Tablets (Generic Bupropion Hydrochloride SR Tablets) Bupron SR tablets are manufactured by Sun Pharmaceutical Industries Limited, India in the strength of 150 mg. ( Website: https://sunpharma.com/ https://sunpharma.com/ ) URL: https://www.clearskypharmacy.biz/generic-zyban-sr-bupron-sr-by-sun-pharma.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

6. Bupron SR Tablets (Generic Bupropion Hydrochloride SR Tablets) Bupropion Hydrochloride Tablets – Brand Names Bupropion Hydrochloride is available under various drug trade names that include Wellbutrin, Wellbutrin SR, Wellbutrin XL, Bupron XL, Bupron SR, Nicotex, Nicotex SR, Smoquit -SR, Aplenzin, Buproban, Forfivo XL, Bupdep, Bupep SR, Bupep SR 150 Bupropion, Bupron, Budeprion, Budeprion SR, Prexaton, Elontril, Aplenzin, Zyban Advantage, and Zyban. © Clearsky Pharmacy ( www.clearskypharmacy.biz )

7. Bupron SR Tablets (Generic Bupropion Hydrochloride SR Tablets) Uses of Bupron SR Tablets Bupron SR tablets (Bupropion Hydrochloride extended-release tablets, USP (SR)) are an aminoketone agent used as part of a support program as an aid to smoking cessation treatment. Bupropion is also used to treat depression and to prevent depression in patients with seasonal affective disorder (SAD), which is sometimes called winter depression. It is also help people stop smoking. Bupropion Hydrochloride belongs to a class of medications called antidepressants. It works by increasing certain types of activity in the brain. In comparison to several other antidepressants, it does not cause as much weight gain or sexual dysfunction. This medicine is not indicated for use in patients below the age of 18 years. URL: https://www.clearskypharmacy.biz/generic-zyban-sr-bupron-sr-by-sun-pharma.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

8. Bupron SR Tablets (Generic Bupropion Hydrochloride SR Tablets) Bupron SR Tablets Dosage The recommended adult Oral dosage of Bupron SR tablets (Bupropion Hydrochloride SR tablets) for smoking cessation treatment is given below: Starting dose: Starting dose: 150 mg per day for first 3 days. Increase dose gradually to reduce seizure risk. Begin dosing one week before quit day. After 3 days, increase the dose to 300 mg per day, given as 150 mg twice daily at an interval of at least 8 hours. May be used with a nicotine transdermal system. Moderate to severe hepatic impairment: Moderate to severe hepatic impairment: 150 mg every other day. Mild hepatic impairment: Consider reducing the dose and/or frequency of dosing. Renal impairment: Renal impairment: Consider reducing the dose and/or frequency. Bupron SR tablets © Clearsky Pharmacy ( www.clearskypharmacy.biz )

9. Bupron SR Tablets (Generic Bupropion Hydrochloride SR Tablets) Contraindications Bupron SR tablets are contraindicated in patients with known hypersensitivity to Bupropion Hydrochloride or any inactive ingredient present in Bupron SR tablets. Bupron SR Tablets (Generic Bupropion Hydrochloride SR Tablets) should not be given to patients who have a Seizure disorder, Current or prior diagnosis of bulimia or anorexia nervosa or in cases of abrupt discontinuation of alcohol, benzodiazepines, barbiturates, antiepileptic drugs. Bupropion Hydrochloride is also contraindicated in a patient who is being treated with linezolid or intravenous methylene blu. URL: https://www.clearskypharmacy.biz/generic-zyban-sr-bupron-sr-by-sun-pharma.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

10. Bupron SR Tablets (Generic Bupropion Hydrochloride SR Tablets) Storage Instructions Bupron SR Tablets (Generic Bupropion Hydrochloride SR Tablets) have to be stored at controlled room temperature i.e. from 20°C to 25°C (68°F to 77°F) with excursions permitted between 15° to 30°C (59° to 86°F). Keep this as well as all other medicines away from children and pets. URL: https://www.clearskypharmacy.biz/generic-zyban-sr-bupron-sr-by-sun-pharma.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

11. Bupron SR Tablets (Generic Bupropion Hydrochloride SR Tablets) Warnings Neuropsychiatric adverse events during smoking cessation: Postmarketing reports of serious or clinically significant neuropsychiatric adverse events have included changes in mood (including depression and mania), psychosis, hallucinations, paranoia, delusions, homicidal ideation, aggression, hostility, agitation, anxiety, and panic, as well as suicidal ideation, suicide attempt, and completed suicide. Observe patients attempting to quit smoking with Bupropion for the occurrence of such symptoms and instruct them to discontinue bupropion and contact a healthcare provider if they experience such adverse events. Seizure risk: The risk is dose-related. Can minimize risk by gradually increasing the dose and limiting daily dose to 300 mg. Discontinue if seizure occurs. © Clearsky Pharmacy ( www.clearskypharmacy.biz )

12. Bupron SR Tablets (Generic Bupropion Hydrochloride SR Tablets) Warnings Hypertension: Bupron SR (Generic Bupropion Hydrochloride SR 150 mg tablets) can increase blood pressure. Monitor blood pressure before initiating treatment and periodically during treatment. Activation of mania/hypomania: Screen patients for bipolar disorder and monitor for these symptoms. Psychosis and other neuropsychiatric reactions: Instruct patients to contact a healthcare professional if such reactions occur. Depressed patients treated with Bupron SR have had a variety of neuropsychiatric signs and symptoms, including delusions, hallucinations, psychosis, concentration disturbance, paranoia, and confusion. Angle-closure glaucoma: Angle-closure glaucoma has occurred in patients with untreated anatomically narrow angles treated with antidepressants URL: https://www.clearskypharmacy.biz/generic-zyban-sr-bupron-sr-by-sun-pharma.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

13. Bupron SR Tablets (Generic Bupropion Hydrochloride SR Tablets) Side Effects Most common Bupropion Hydrochloride (Bupron SR tablets) side effects with an incidence rate of 5% and at least 2% more than placebo rate are: headache, dry mouth, nausea, insomnia, dizziness, pharyngitis, constipation, agitation, anxiety, abdominal pain, tinnitus, tremor, palpitation, myalgia, sweating, rash, and anorexia. URL: https://www.clearskypharmacy.biz/generic-zyban-sr-bupron-sr-by-sun-pharma.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

14. Bupron SR Tablets (Generic Bupropion Hydrochloride SR Tablets) Overdose Seizure was reported in approximately one-third of all Bupropion Hydrochloride (Bupron SR tablets) overdose cases. Other serious reactions reported with overdoses of bupropion alone included hallucinations, loss of consciousness, mental status changes, sinus tachycardia, ECG changes such as conduction disturbances (including QRS prolongation) or arrhythmias, clonus, myoclonus, and hyperreflexia. Fever, muscle rigidity, rhabdomyolysis, hypotension, stupor, coma, and respiratory failure have been reported mainly when bupropion was part of multiple drug overdoses. Although most patients recovered without sequelae, deaths associated with overdoses of bupropion alone have been reported in patients ingesting large doses of the drug. Multiple uncontrolled seizures, bradycardia, cardiac failure, and cardiac arrest prior to death were reported in these patients. © Clearsky Pharmacy ( www.clearskypharmacy.biz )

15. Bupron SR Tablets (Generic Bupropion Hydrochloride SR Tablets) Overdose There are no known antidotes for Bupropion Hydrochloride (Bupron SR tablets). In case of an overdose, provide supportive care, including close medical supervision and monitoring. Consider the possibility of multiple drug overdose. Ensure an adequate airway, oxygenation, and ventilation. Monitor cardiac rhythm and vital signs. Induction of emesis is not recommended. URL: https://www.clearskypharmacy.biz/generic-zyban-sr-bupron-sr-by-sun-pharma.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

16. Bupron SR Tablets (Generic Bupropion Hydrochloride SR Tablets) Bupron SR Tablets During Pregnancy Bupropion Hydrochloride (Bupron SR tablets) is classified by the US FDA as Pregnancy Category C. Data from epidemiological studies including pregnant women exposed to Bupropion in the first trimester indicate no increased risk of congenital malformations overall. No clear evidence of teratogenic activity was found in reproductive developmental studies conducted in rats and rabbits. However, in rabbits, slightly increased incidences of fetal malformations and skeletal variations were observed at doses approximately equal to the maximum recommended human dose (MRHD) and greater and decreased fetal weights were seen at doses twice the MRHD and greater. URL: https://www.clearskypharmacy.biz/generic-zyban-sr-bupron-sr-by-sun-pharma.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

17. Bupron SR Tablets (Generic Bupropion Hydrochloride SR Tablets) Bupron SR Tablets During Pregnancy This medicine should be used during pregnancy only if the potential benefit outweighs the potential risk to the fetus. Neonates exposed to this drug late in the third trimester may require respiratory support, tube feeding, and/or prolonged hospitalization. Exposed neonates should be monitored after delivery for direct toxic effects of this medicine. URL: https://www.clearskypharmacy.biz/generic-zyban-sr-bupron-sr-by-sun-pharma.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

18. Bupron SR Tablets (Generic Bupropion Hydrochloride SR Tablets) For more details on Bupron SR Tablets click here Bupron SR Tablets click here Bupron SR Tablets (Bupropion Hydrochloride SR Tablets) by Sun Pharmaceutical Industries Limited, India. URL: https://www.clearskypharmacy.biz/generic-zyban-sr-bupron-sr-by-sun-pharma.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )