Betnovate Cream (Generic Betamethasone Valerate Cream)

1. Betnovate Cream (Generic Betamethasone Valerate Cream) © Clearsky Pharmacy ( www.clearskypharmacy.biz )

2. Betnovate Cream (Generic Betamethasone Valerate Cream) © Clearsky Pharmacy ( www.clearskypharmacy.biz )

3. Betnovate Cream (Generic Betamethasone Valerate Cream) Betnovate Cream (Generic Betamethasone Valerate Cream) belongs to a group of medicines known as corticosteroids, and is used to treat various inflammatory skin conditions, including eczema, psoriasis, dermatitis, insect bites and prickly heat. Betamethasone Valerate Cream works by reducing the inflammation in the affected area to reduce the redness, swelling and itchiness of the skin. © Clearsky Pharmacy ( www.clearskypharmacy.biz )

4. Betnovate Cream (Generic Betamethasone Valerate Cream) Active Ingredient The active ingredient present in Betnovate Cream is Betamethasone Valerate. Each gram of the cream contains contains 1.2 mg Betamethasone Valerate (equivalent to 1 mg Betamethasone). © Clearsky Pharmacy ( www.clearskypharmacy.biz )

5. Betnovate Cream (Generic Betamethasone Valerate Cream) Chemical Structure The structure of Betamethasone Valerate is given below: © Clearsky Pharmacy ( www.clearskypharmacy.biz )

6. Betnovate Cream (Generic Betamethasone Valerate Cream) Betnovate Cream is manufactured by GlaxoSmithKline Pharmaceuticals Limited, India is available in the strengths of 0.10% W/W and is available as a 20 gm tube. (Website: https://india-pharma.gsk.com/ https://india-pharma.gsk.com/ ) URL: URL: https://www.clearskypharmacy.biz/betnovate-cream.html https://www.clearskypharmacy.biz/betnovate-cream.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

7. Betnovate Cream (Generic Betamethasone Valerate Cream) Betamethasone Valerate Cream – Brand Names Betamethasone Valerate Cream is available under various drug trade names that include Betnovate, Betnowell, Fucibet, Walacort. Also available as a combination like Betnovate-C, Betnovate-S and Betnovate-GM. URL: URL: https://www.clearskypharmacy.biz/betnovate-cream.html https://www.clearskypharmacy.biz/betnovate-cream.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

8. Betnovate Cream (Generic Betamethasone Valerate Cream) Uses of Betnovate Cream Betnovate Cream (Betamethasone Valerate Cream) is used to treat a variety of skin conditions such as eczema, dermatitis, allergies, rash, redness, itching, swelling, or other discomfort caused by skin conditions. Betamethasone reduces the swelling, itching, and redness that can occur in these types of conditions. This medication is a medium-strength corticosteroid (cortisone-like medicine or steroid). URL: URL: https://www.clearskypharmacy.biz/betnovate-cream.html https://www.clearskypharmacy.biz/betnovate-cream.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

9. Betnovate Cream (Generic Betamethasone Valerate Cream) Uses of Betnovate Cream Betamethasone Valerate is a potent topical corticosteroid indicated for adults, elderly and children over 1 year for the relief of the inflammatory and pruritic manifestations of steroid responsive dermatoses. These include the following: Atopic dermatitis (including infantile atopic dermatitis) Nummular dermatitis (discoid eczema) Prurigo nodularis Psoriasis (excluding widespread plaque psoriasis) Lichen simplex chronicus (neurodermatitis) and lichen planus Seborrhoeic dermatitis Irritant or allergic contact dermatitis Discoid lupus erythematosus Adjunct to systemic steroid therapy in generalised erythroderma Insect bite reactions © Clearsky Pharmacy ( www.clearskypharmacy.biz )

10. Betnovate Cream (Generic Betamethasone Valerate Cream) Betnovate Cream Dosage The dosage of Betnovate Cream Betnovate Cream (Betamethasone Valerate Cream) is given below: Apply a thin layer of Betnovate Cream once or twice daily and gently rub in, using only enough to cover the entire affected area. Wash your hands after use unless treating the hands. Do not use this medicine on large areas of the body for a long time (such as every day for many weeks or months). Use Betnovate cream at about the same time each day. Using it at the same time each day will have the best effect. URL: URL: https://www.clearskypharmacy.biz/betnovate-cream.html https://www.clearskypharmacy.biz/betnovate-cream.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

11. Betnovate Cream (Generic Betamethasone Valerate Cream) Betnovate Cream Dosage The dosage of Betnovate Cream Betnovate Cream (Betamethasone Valerate Cream) is given below: Only use Betnovate cream for as long as your doctor recommends. In case the condition worsens or does not improve within two to four weeks, talk to your doctor. Occlusive dressings may be used for the management of psoriasis or recalcitrant conditions. If an infection develops, the use of occlusive dressings should be discontinued and appropriate antimicrobial therapy instituted. URL: URL: https://www.clearskypharmacy.biz/betnovate-cream.html https://www.clearskypharmacy.biz/betnovate-cream.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

12. Betnovate Cream (Generic Betamethasone Valerate Cream) Contraindications Betnovate Cream is contraindicated in persons with a hypersensitivity (allergy) to Betamethasone Valerate or any of the other ingredients of this medicine. The following conditions should not be treated with Betamethasone Valerate cream: Untreated cutaneous infections, Rosacea, Acne vulgaris, Pruritus without inflammation, Perianal and genital pruritus and Perioral dermatitis. Betamethasone valerate is also contraindicated in dermatoses in infants under one year of age, including dermatitis. URL: URL: https://www.clearskypharmacy.biz/betnovate-cream.html https://www.clearskypharmacy.biz/betnovate-cream.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

13. Betnovate Cream (Generic Betamethasone Valerate Cream) Storage Instructions Betnovate Cream (Betamethasone Valerate Cream) have to be stored at controlled room temperature i.e. from 20°C to 25°C (68°F to 77°F) with excursions permitted between 15° to 30°C (59° to 86°F). Keep this as well as all other medicines away from children and pets. URL: URL: https://www.clearskypharmacy.biz/betnovate-cream.html https://www.clearskypharmacy.biz/betnovate-cream.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

14. Betnovate Cream (Generic Betamethasone Valerate Cream) Warnings Systemic absorption of topical corticosteroids has produced reversible hypothalamic-pituitary-adrenal (HPA) axis suppression, manifestations of Cushing's syndrome, hyperglycemia, and glucosuria in some patients. Conditions which augment systemic absorption include the application of the more potent steroids, use over large surface areas, prolonged use, and the addition of occlusive dressings. Therefore, patients receiving a large dose of a potent topical steroid applied to a large surface area should be evaluated periodically for evidence of HPA axis suppression. In case HPA axis suppression is noted, an attempt should be made to withdraw the drug, to reduce the frequency of application, or substitute to a less potent steroid. URL: URL: https://www.clearskypharmacy.biz/betnovate-cream.html https://www.clearskypharmacy.biz/betnovate-cream.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

15. Betnovate Cream (Generic Betamethasone Valerate Cream) Warnings Recovery of HPA axis function is generally prompt and complete upon discontinuation of the medicine. Infrequently, signs and symptoms of steroid withdrawal may occur, requiring supplemental systemic corticosteroids. Suitable precautions should be taken when using topical corticosteroids in patients with stasis dermatitis and other skin diseases with impaired circulation. Topical corticosteroids should be used with caution on lesions close to the eye because systemic absorption may cause increased intraocular pressure, glaucoma or cataracts. URL: URL: https://www.clearskypharmacy.biz/betnovate-cream.html https://www.clearskypharmacy.biz/betnovate-cream.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

16. Betnovate Cream (Generic Betamethasone Valerate Cream) Warnings Pediatric patients may absorb proportionally larger amounts of topical corticosteroids and thus be more susceptible to systemic toxicity. In case irritation develops, topical corticosteroids should be discontinued and appropriate therapy instituted. In the presence of dermatological infections, the use of an appropriate antifungal or antibacterial agent should be instituted. If a favorable response does not occur promptly, the corticosteroid should be discontinued until the infection has been adequately controlled. Do not use if there is an infection or sore in the area to be treated. URL: URL: https://www.clearskypharmacy.biz/betnovate-cream.html https://www.clearskypharmacy.biz/betnovate-cream.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

17. Betnovate Cream (Generic Betamethasone Valerate Cream) Betnovate Cream Side Effects The following local side effects are reported infrequently with topical corticosteroids, but may occur more frequently with the use of occlusive dressings. These reactions are listed in an approximate decreasing order of occurrence: Burning, Itching, Irritation, Dryness, Folliculitis, Hypertrichosis, Acneiform eruptions, Hypopigmentation, Perioral dermatitis, allergic contact dermatitis, Maceration of the skin, Secondary infection, Skin Atrophy, Striae and Miliaria. URL: URL: https://www.clearskypharmacy.biz/betnovate-cream.html https://www.clearskypharmacy.biz/betnovate-cream.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

18. Betnovate Cream (Generic Betamethasone Valerate Cream) Overdose Topically applied corticosteroids like Betnovate cream can be absorbed in sufficient amounts to produce systemic effects. Excessive prolonged use may suppress hypothalamic-pituitary-adrenal (HPA) axis function, resulting in secondary adrenal insufficiency, which is usually reversible. Excessive prolonged use may also produce manifestations of hypercorticisim, including Cushing's disease. Acute overdosage is very unlikely to occur, however, in the case of chronic overdosage or misuse the features of hypercortisolism may occur. In the event of overdose, Betamethasone Valerate should be withdrawn gradually by reducing the frequency of application, or by substituting a less potent corticosteroid because of the risk of glucocorticosteroid insufficiency. URL: URL: https://www.clearskypharmacy.biz/betnovate-cream.html https://www.clearskypharmacy.biz/betnovate-cream.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

19. Betnovate Cream (Generic Betamethasone Valerate Cream) Betnovate Cream During Pregnancy Betnovate Cream (Betamethasone Valerate Cream) has been classified by the US FDA as Pregnancy Category C. Corticosteroids are generally teratogenic in laboratory animals when administered systemically at relatively low dosage levels. Some corticosteroids have been shown to be teratogenic after dermal application in laboratory animals. There are no adequate and well-controlled studies in pregnant women on teratogenic effects from topically applied corticosteroids like Betnovate Cream. Therefore, topical corticosteroids like Betamethasone Valerate cream should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Medicines of this class should not be used extensively in large amounts or for prolonged periods of time in pregnant patients. URL: URL: https://www.clearskypharmacy.biz/betnovate-cream.html https://www.clearskypharmacy.biz/betnovate-cream.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

20. Betnovate Cream (Generic Betamethasone Valerate Cream) Betnovate Cream (Generic Betamethasone Valerate Cream) by GlaxoSmithKline Pharmaceuticals Limited, India. URL: URL: https://www.clearskypharmacy.biz/betnovate-cream.html https://www.clearskypharmacy.biz/betnovate-cream.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )