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South Yorkshire Cohort Research: Managing Weight & Long-Term Conditions

The South Yorkshire Cohort conducts research on managing weight and long-term conditions, exploring key variables from an NHS perspective. The program involves observational cohort recruitment, outcome measurement, and multiple RCTs. Milestones include NHS ethics approval, GP recruitment, and collaborative studies. Future goals include maximizing representativeness, identifying trials, securing long-term funding, and linking with routine data.

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South Yorkshire Cohort Research: Managing Weight & Long-Term Conditions

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  1. South Yorkshire Cohort Principal Investigator: Paul Bissell Project manager: Clare Relton ScHARR (Public Health) University of Sheffield

  2. Purpose • Programme of research into management of weight and long term conditions • Relationship between key variables from NHS perspective • Facility • multiple cohort trials • multiple studies

  3. Methods • Recruitment large observational cohort of patients with condition(s) of interest • Regular outcome measurement of whole cohort • Capacity for multiple RCTs and studies

  4. Recruitment Two stage 40 GP practices Mail out to 144,000 patients Invitation from GP Health Questionnaire SAE Online form

  5. GP Invitation letter = Patient Information Sheet

  6. Milestones • NHS Research Ethics Committee approval • 30 GPs recruited • 18,400 returned Health Questionnaires • 5 collaborative studies active/ completed • 6+ studies coming onstream in 2013 including one cmRCT (additional income)

  7. SYC Collaborative studies – how does it work? • SYC database search • Research proposal form – SYC mgmt • Cost • Leeds East REC (guardians of the cohort)

  8. SYC Collaborative studies

  9. Future • Maximising representativeness • Unknown attrition • Identifying trials in design stage • Long term funding for infrastructure • Linkage with routine data

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