Understanding Dominant Alleles and Recessive Lethality: Genetic Interactions Explained
This overview explores the complexities of dominant alleles exhibiting recessive lethality and the nuances of genes with multiple alleles. It covers various dominance relationships, including complete dominance, incomplete dominance, codominance, and the hierarchy of dominance in genes such as IA, IB, and others. The description also touches on epistasis versus suppression and the interactions of unknown genes and environmental factors affecting phenotype expression, highlighting the concepts of lack of penetrance and variable expressivity in genetics.
Understanding Dominant Alleles and Recessive Lethality: Genetic Interactions Explained
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Presentation Transcript
(black) Dominant allele with recessive lethality
1 gene with 2 alleles we’ve seen 4 cases: Dominant allele with recessive lethality 1 AA : 2 Aa : 1 aa complete dom/rec dom dom rec incomplete dominance dom blend dom-rec rec codominant dom1 dom1+ dom2 dom2 recessive lethal (dom. marker) dead dom rec
IC. Genes with multiple alleles 1 Gene with 3 alleles IA & IB are co-dominant; i is recessive
IC. Genes with multiple alleles Hierarchy of dominance: C > cch > ch > c
IC. Genes with multiple alleles chinchilla cch
IC. Genes with multiple alleles chinchilla cch
IC. Genes with multiple alleles chinchilla cch himalayan ch
IC. Genes with multiple alleles Hierarchy of dominance: C > cch > ch > c
IC. Genes with multiple alleles A short list of the 1587 known mutant alleles of the Drosophila melanogaster eye color gene w (white)
ID. Two genes, interacting Back to 2 genes TIME
A/A ; B/B a/a ; b/b A/a ; B/b self-cross A/_ ; B/_ A/_ ; b/b a/a ; B/_ a/a ; b/b
ww m+ & m
Coat color: Genes A, B, C, D, E, S
cc C
III. Genotype -> Phenotype . . . but with interactions of unknown other genes, environment, + . . .
Lack of Penetrance Variable Expressivity Lack of Penetrance