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Improving Punctum Plug Retention

Improving Punctum Plug Retention. Jennifer Langh. Current Drug Delivery Methods. Why focus on improving retention?. Lab Set-Up. DOE Software. Water -in-oil-in-water (w/o/w) double emulsion technique. In-line Homogenizer. In-line Homogenizer Rotor Stators. Injection Needles.

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Improving Punctum Plug Retention

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  1. Improving Punctum Plug Retention Jennifer Langh

  2. Current Drug Delivery Methods

  3. Why focus on improving retention?

  4. Lab Set-Up

  5. DOE Software

  6. Water-in-oil-in-water (w/o/w) double emulsion technique

  7. In-line Homogenizer

  8. In-line Homogenizer Rotor Stators

  9. Injection Needles

  10. Particle Size Analyzer

  11. SEM : Scanning Electron Microscope

  12. Formulation of Punctum Plug

  13. In-Vitro Release Studies

  14. Clinical Trials • Animal Studies • Human Studies

  15. Work Cited • Double Emulsion Device. Digital image. SoftMatter RSS. N.p., n.d. Web. 10 Aug. 2014. • Drug Delivery through Conventional and Novel Delivery System. Digital image. PHEMA Hydrogels: Devices for Ocular Drug Delivery Tomar N, Tomar M, Gulati N, Nagaich U - Int J Health Allied Sci. N.p., n.d. Web. 10 Aug. 2014. • Environmentally Controlled Area for Sensitive Printing Process and Equipment. Digital image. Cleanrooms & Controlled Environments. N.p., n.d. Web. 10 Aug. 2014. • High Shear Mixer/In-line. Digital image. High Shear Mixer / In-line. N.p., n.d. Web. 10 Aug. 2014. • Homogenizer Rotor Stators. Digital image. ART ProzessLabortechnik GmbH Co KG HomogenisierenDispergierenMischen Products Comments. N.p., n.d. Web. 10 Aug. 2014. • Injection Cannula. Digital image. NewSurg, Inc.N.p., n.d. Web. 10 Aug. 2014. • In-Vitro release profile. Digital image. Auritec Pharmaceuticals - In Vitro. N.p., n.d. Web. 10 Aug. 2014. • JMP Software Logo. Digital image. SAS JMP Statistical Software | UL Lafayette CIO Office. N.p., n.d. Web. 10 Aug. 2014. • LS™ 13 320 SW. Digital image. Beckman Coulter. N.p., n.d. Web. 10 Aug. 2014. • Microparticles SEM image. Digital image. NanomiMonosphere Technology. N.p., n.d. Web. 10 Aug. 2014. • OTX-DP release over time. Digital image. Pharmacokinetics Demonstrating Sustained Dexamethasone Delivery from a Punctum Plug in a Canine Model -- Desai Et Al. 54 (6): 1089 -- ARVO Meeting Abstracts. N.p., n.d. Web. 10 Aug. 2014. • OTX-TP Inserted Into the Vertical Canaliculus. Digital image. 90 DAY CANINE TOXICITY STUDY DEMONSTRATING THE SAFETY OF A SUSTAINED RELEASE TRAVOPROST PUNCTUM PLUG. N.p., n.d. Web. 10 Aug. 2014. • OTX-TP1 Product Design. Digital image. 90 DAY CANINE TOXICITY STUDY DEMONSTRATING THE SAFETY OF A SUSTAINED RELEASE TRAVOPROST PUNCTUM PLUG. N.p., n.d. Web. 10 Aug. 2014. • Punctum Plug Depot. Digital image. Ocular Therapeutix Inc. N.p., n.d. Web. 10 Aug. 2014. • Scanning Electron Microscope. Digital image. Union College Geology Department, Kurt Hollocher, Scanning Electron Microscope, Shared Facility. N.p., n.d. Web. 10 Aug. 2014. • SEM Photographs. Digital image. IJMS | Free Full-Text | Preparation of Chitosan and Water-Soluble Chitosan Microspheres via Spray-Drying Method to Lower Blood Lipids in Rats Fed with High-Fat Diets | HTML. N.p., n.d. Web. 10 Aug. 2014. • T-E-A-M. Digital image. KLeadtv. N.p., n.d. Web. 10 Aug. 2014. • Working Diagram of Inline Homogenizer. Digital image. Top-grade Bitumen Homogenizing Pump, View Pump, TONGSHENG Product Details from Zhejiang Xingsheng Machinery Co., Ltd. on. N.p., n.d. Web. 10 Aug. 2014.

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