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Regionala medicinska programgruppen

Regionala medicinska programgruppen. Hjärtsvikt. Kort genomgång av aktualiteter. Kronisk hjärtsvikt Uppdaterat PM Paradigm CRT/ICD Heartmate Consensus vid övertagning Kardiomyopati Hypertrof Etanolablation Non compaction Diagnostik Peripartum Europeiska registret.

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Regionala medicinska programgruppen

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  1. Regionala medicinska programgruppen Hjärtsvikt

  2. Kort genomgång av aktualiteter • Kronisk hjärtsvikt • Uppdaterat PM • Paradigm • CRT/ICD • Heartmate • Consensus vid övertagning • Kardiomyopati • Hypertrof • Etanolablation • Non compaction • Diagnostik • Peripartum • Europeiska registret

  3. Behandling av kronisk hjärtsvikt vid kardiologiska kliniken • Uppdateringar • Resonemang om • mekanismer • måldoser/målvärden • järnterapi • vätskekarens

  4. PARADIGM PARADIGM-HF is a randomized, double-blind, Phase III outcome study evaluating the efficacy and safety profile of LCZ696 versus enalaprilin 8,436 patients with heart failure with reduced ejection fraction

  5. Paradigm forts The primary outcome is a composite of time to first occurrence of either cardiovascular death or heart failure hospitalization, and the trial is also designed to be able to detect a significant difference in cardiovascular death

  6. Paradigm forts Data Monitoring Committee (DMC) unanimously recommends early closure confirming combined primary endpoint met - LCZ696 delayed cardiovascular death and reduced heart failure hospitalizations vs. enalapril

  7. CRT/ICD • Försök till mera strukturerad optimering av CRT • Följa guidelines för ICD – vi har nog underutnyttjat metoden

  8. Heartmate

  9. Heartmate, forts • Används redan som destinationsterapi i Sverige • Svensk studie på g

  10. Heartmate forts

  11. Gravt hjärtsviktande patienter i regionen – internt mail

  12. Alkoholablation (PTSMA) Percutaneous transluminal septal myocardial ablation, PTSMA

  13. Alkoholablation - indikationer • NYHA klass III-IV trots optimal medicinsk behandling • Utflödesgradient i vila eller arbete ≥ 50 mmHg • Septumstjocklek ≥18 mm

  14. Multidiciplinärt!

  15. PTSMA – resultat- maj 20148 patienter

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