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Patient 8. Patient 9. +4. +6. +6,+6. +10. +6,+10. +6,+10,+17. +6,+6,+10. Hematologic CR (1282/07) Total of abn nuclei: 13%. P (2385/95) Total of abn nuclei: 75.8%. +4,+6. +4,+6. +4,+10. +4,+10. +4,+6,+10. +4,+6,+10. +6,+10,+10. +6,+10,+10. +4,+6,+6,+10. +4,+6,+6,+10. +4.

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  1. Patient 8 Patient 9 +4 +6 +6,+6 +10 +6,+10 +6,+10,+17 +6,+6,+10 Hematologic CR (1282/07) Total of abn nuclei: 13% P (2385/95) Total of abn nuclei: 75.8% +4,+6 +4,+6 +4,+10 +4,+10 +4,+6,+10 +4,+6,+10 +6,+10,+10 +6,+10,+10 +4,+6,+6,+10 +4,+6,+6,+10 +4 +4 +6 +6 +17 +17 Relapse (1181/0) Total of abn nuclei: 57.3% +4 +6 +6,+6 +10 +6,+10 +6,+10,+17 +6,+6,+10 +4,+6 +4,+17 +6,+10 +6,+17 Relapse I (1527/97) Total of abn nuclei: 78.3% +4 +6 +6,+6 +10 +6,+10 +6,+10,+17 +6,+6,+10 +10 +4,+10 +10,+17 +4,+6,+10 +4,+6,+17 +4,+10,+17 +6,+10,+17 +4,+6,+10,+17 +4+4 +4,+6,+10,+10 +4,+4,+6,+10 +4,+6 +4,+10 +4,+6,+10 +6,+10,+10 +4,+6,+6,+10 +6,+10 +4,+6 +4,+17 +6,+10 +6,+17 +10 +6,+10 +10,+17 +4+4 +4,+6,+10,+10 +4,+4,+6,+10 Relapse II (27/98) Total of abn nuclei: 25.8% Hematologic CR (29/09) Total of abn nuclei: 1.4% -- +10 +6,+10 +10,+17 +4 +6 +6,+6 +10 +6,+10 +6,+10,+17 +6,+6,+10 -- Hematologic CR (540/09) Total of abn nuclei: 0.6% +4,+6 +4,+10 +4,+6,+10 +6,+10,+10 +4,+6,+6,+10 Relapse III (158/98) Total of abn nuclei: 3.2% +4+4 +4,+6,+10,+10 +4,+4,+6,+10 Patient 10 P (388/02) Total of abn nuclei: 50.4% <1% >1% new >1% 0 % Relapse (95/03) Total of abn nuclei: 22.6%

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