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Organizations’ Official Statements/Guidelines on IV tPA Use: What Do They Suggest is the Emergency Medicine Standard PowerPoint Presentation
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Organizations’ Official Statements/Guidelines on IV tPA Use: What Do They Suggest is the Emergency Medicine Standard of Care?. 2006 Advanced Emergency & Acute Care Medicine and Technology Conference. Emergency Medicine Associates Atlantic City, NJ September 26-27, 2006.

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Presentation Transcript
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Organizations’ Official Statements/Guidelines on IV tPA Use: What Do They Suggest is the Emergency Medicine Standard of Care?
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William Dalsey, MD, FACEPChairman Department of Emergency MedicineKimball Medical Center Lakewood, NJ
disclosures
Disclosures
  • All past advisory board or speakers’ bureau activities have expired within the past year
global objectives
Global Objectives
  • Maximize patient outcomes
  • Utilize health care resources well
  • Optimize evidence-based medicine
  • Enhance ED practice
case presentation
Case Presentation
  • 52 year old male
  • Dysarthria and right-sided weakness
  • Sudden onset without progression
  • BGM 80
  • VS: HR 85 BP 185/95 RR 16
case presentation8

Case Presentation…

Minimal dysarthria and slight dominant right

hand/leg weakness

Chairman of Plastic Surgery

Hx: Hypertention, smoker

FH: CAD and CVA

No evidence trauma or toxicity

ECG NSR without evidence of AMI or

arrythmia

cva management
CVA Management
  • What would you do?
  • What did the EP do?
acep tpa policy

ACEP tPA Policy

tPA may be efficacious therapy when used incorporating the guidelines established by the NINDS Trial

Commitment of hospital administration, neurology, neurosurgery, ED, radiology and laboratory to ensure the systems necessary for safe use

what policies statements from other em organizations say

What Policies/Statements From Other EM Organizations Say?

Society of Academic Emergency Medicine 2003

Insufficient Data for SOC, Barriers, Research

Canadian Assoc of Emergency Physicians 2001

CT Interpretations, Cleveland, Time to Rx

American Academy of Emergency Medicine

Not SOC-Selection Bias

what about non em organizations

What About Non-EM Organizations?

NINDS 2002/2005

AHA 2000/2005

ACCP 2005

ACCS 2004

AAN,ASA 2002

additional literature

Additional Literature?

NINDS Reanalysis, subanalysis

Additional Prospective Data

Data Registry Reports

Meta Analysis

Cochrane Collaboration

Compare the results with a conventional training protocol. Most people do at least two exercises per muscle group, perform three sets and perhaps 12 or 15 reps per set. Allowing just five seconds per rep, that makes for at least 36 minutes of exercise per workout.

This is usually done three times per week. So in six weeks, a conventional program would involve 648 minutes of exercise. That's 42 times more than the subjects in our study. Are your results in the last six weeks 42 times better than theirs? I doubt it.

Remember, these golfers were exercising in a way that did not involve stretching or moving the weight over a full range of motion. So how did this affect a full range of motion activity like a golf drive?

Every one of them showed an improvement. The increase in drive distance varied from 5 to 31 yards. Keep in mind that these subjects had been golfing for up to 40 years and had handicaps as low as eleven. So getting any improvement in golfers who already play at this level is impressive. Getting it with 14 minutes of exercise spread over six weeks is truly revolutionary.

The fact is every sport -- even a finesse sport like golf -- is improved by an increase in strength. Muscles are responsible for all movement in the body and stronger muscles deliver more power to every aspect of movement, irrespective of its range of motion.

Since this study, I've gone on to improve this method of training. Further research showed that static hold times could be reduced to even less than what the golfers used. Workouts can be spaced further apart as a trainee gets stronger. I work with advanced trainees who train once every six weeks, yet they gain strength on every exercise each time they work out. The weights they hoist are enormous.

I believe the time is coming when most people will have a better understanding of the role of proper, efficient strength training methods and frequency. For the guy who wants maximum results with minimum time invested, an ultra-brief but ultra-intense workout will be performed about as often as he gets a haircut. Anything more is just lifting weights as a busy work hobby.

Train smart!

impact of guidelines policies

Impact of Guidelines/Policies

Education and Training

Litigation

Resource Support

System Development

Public Notification

Stroke Center Certification

what other issues do the guidelines policies address

What Other Issues Do the Guidelines/Policies Address?

Designated Stroke Teams/Systems

Use of Clinical Pathways/Protocols

Training Dedicated Stroke Nurses

Time to CT and Interpretation

Use of Aspirin

BP Control

Prevention Recurring Stroke

Cephalgia

Migraine or temporal arteritis

Seizure disorders

Akinetic seizure or partial lobe epilepsy

CNS space-occupying lesions

ENT, ophthomologic pathology

what other issues do the guidelines policies address16
What Other Issues Do the Guidelines/Policies Address??
  • Prevention of UTI, skin ulcers, aspiration pneumonia, DVT and PE
  • Early Rehabilitation and Physical Therapy
  • Lack of Efficacy Heparin
  • Blood Glucose Control
  • Lack of Efficacy Neuroprotective Agents
where do i believe the guidelines policies leave us

Where Do I Believe the Guidelines/Policies Leave Us?

tPA should be considered for appropriate patients when the NINDS criteria for safe use can be achieved

Patients and families should know the risks/benefits of tPA before it is given

Careful documentation of the medical record in necessary for every case

case presentation18
Case Presentation
  • So what happened?
questions
Questions?

www.FERNE.org

sparkledmd@aol.com

ferne_ema_2006_dalsey_tpastatements_092606_final.cd

3/12/2014 11:27 AM