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This study investigates the gene expression profiles across various cancer cell lines, including SK-Mel-103, HT-29, A549, HCT-116, OVCAR-8, MDA-MB231, PC3, and NCI-H460. Using techniques such as shRNA screening, we aim to identify critical genes associated with cancer progression and drug response. The diverse cell lines represent various types of cancers, providing a comprehensive overview of gene interactions and potential therapeutic targets. Results could enhance understanding of tumor biology and improve treatment strategies.
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U251 G0/G1 87 G0/G1 63 G0/G1 60 S 6 S 19 S 16 G2/M 22 G2/M 20 G2/M 7 Cell number SK-Mel-103 RDES PI G0/G1 52 G0/G1 42 G0/G1 66 G0/G1 33 G0/G1 70 G0/G1 46 G0/G1 60 G0/G1 53 G0/G1 59 G0/G1 20 G0/G1 53 G0/G1 47 G0/G1 28 G0/G1 45 G0/G1 45 G0/G1 59 G0/G1 49 G0/G1 38 G0/G1 54 G0/G1 50 G0/G1 45 G0/G1 42 G0/G1 48 G0/G1 40 G0/G1 60 S 31 S 34 S 30 S 28 S 19 S 37 S 37 S 25 S 50 S 20 S 17 S 26 S 36 S 23 S 29 S 41 S 16 S 31 S 38 S 38 S 23 S 37 S 17 S 23 S 21 HT-29 G2/M 4 G2/M 23 G2/M 24 G2/M 20 G2/M 36 G2/M 35 G2/M 17 G2/M 13 G2/M 18 G2/M 26 G2/M 6 G2/M 21 G2/M 30 G2/M 24 G2/M 31 G2/M 36 G2/M 26 G2/M 24 G2/M 31 G2/M 17 G2/M 13 G2/M 24 G2/M 17 G2/M 14 G2/M 21 0 25 50 75 100 SAOS-2 A549 HCT-116 18 36 54 72 OVCAR-8 MDA-MB231 PC3 NCI-H460 shRNAs: Cl M1 shRNAs: Cl M3 SK-Mel-173 SK-Mel-147 CACO-2 S5
