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Platelet and global haemostatic effects of common traditional Chinese herbal medicines: implications for anaesthesia. KFJ Ng May 2011. 5. 22 (2000) 13 (2003). 7. 8 (2006) 13 (2005). 7 (2007) 14 (2004). Ann Pharmacother 2004;38:1651. The “Big 3”. Ginkgo biloba (7/29) Garlic (3/29)

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Kfj ng may 2011

Platelet and global haemostatic effects of common traditional Chinese herbal medicines: implications for anaesthesia

KFJ Ng

May 2011


Kfj ng may 2011

5 traditional Chinese herbal medicines:

22 (2000)

13 (2003)

7

8 (2006)

13 (2005)

7 (2007)

14 (2004)


Kfj ng may 2011

Ann Pharmacother 2004;38:1651 traditional Chinese herbal medicines:


The big 3
The “Big 3” traditional Chinese herbal medicines:

  • Ginkgo biloba (7/29)

  • Garlic (3/29)

  • Saw palmetto (2/29)


Ginkgo biloba
Ginkgo biloba traditional Chinese herbal medicines:

Am J Hematol 2005; 79: 343


Ginkgo biloba egb 761
Ginkgo biloba (EGb 761) traditional Chinese herbal medicines:

Thromb Res 2003; 108: 151


Garlic
Garlic traditional Chinese herbal medicines:

A&A 2007; 105: 1214


Garlic1
Garlic traditional Chinese herbal medicines:

Prostaglandins Leukot Essent Fatty Acids 1998;58:257


Saw palmetto
Saw palmetto traditional Chinese herbal medicines:


The big 3 and more
The “Big 3” and more… traditional Chinese herbal medicines:

Plast Reconstr Surg 2007; 120:2044


Fufang compound formula
Fufang (compound formula) traditional Chinese herbal medicines:


Danshen salvia root
Danshen ( traditional Chinese herbal medicines: 丹參, salvia root)


Danshen salvia root1
Danshen ( traditional Chinese herbal medicines: 丹參, salvia root)

Platelets 2008;19:24


Danshen salvia root2
Danshen ( traditional Chinese herbal medicines: 丹參, salvia root)

Thromb Res 2008;123:298


Ligusticum wallichii chuanxiong szechuan lovage
Ligusticum wallichii (chuanxiong, Szechuan lovage, “ traditional Chinese herbal medicines: 川芎”)


Ligusticum wallichii chuanxiong szechuan lovage1
Ligusticum wallichii (chuanxiong, Szechuan lovage, “ traditional Chinese herbal medicines: 川芎”)

Thromb Res 2001;104:15


Curcuma zedoaria zedoary ezhu
Curcuma zedoaria (zedoary, ezhu, “ traditional Chinese herbal medicines: 莪朮”)


Curcuma zedoaria zedoary ezhu1
Curcuma zedoaria (zedoary, ezhu, “ traditional Chinese herbal medicines: 莪朮”)

Thromb Res 2011;127:111


Curcuma zedoaria zedoary ezhu2
Curcuma zedoaria (zedoary, ezhu, “ traditional Chinese herbal medicines: 莪朮”)

Thromb Res 2011;127:111


Angelica sinensis dongguai
Angelica Sinensis (dongguai, “ traditional Chinese herbal medicines: 當歸”)


Dang gui shao yao san dong guai chuanxiong and others
Dang-Gui-Shao-Yao-San ( traditional Chinese herbal medicines: 當歸芍藥散)(dong guai, chuanxiong, and others)

Am J Chin Med 2005;33:747


Radix et rhizoma notoginseng sanqi
Radix et Rhizoma Notoginseng (sanqi, “ traditional Chinese herbal medicines: 三七”)


Radix et rhizoma notoginseng sanqi1
Radix et Rhizoma Notoginseng(sanqi, “ traditional Chinese herbal medicines: 三七”)

J Clin Pharmacol 2000;40:1150


Radix et rhizoma notoginseng sanqi2
Radix et Rhizoma Notoginseng (sanqi, “ traditional Chinese herbal medicines: 三七”)

Pharmacotherapy 2001;21:773


Radix et rhizoma notoginseng sanqi3
Radix et Rhizoma Notoginseng(sanqi, “ traditional Chinese herbal medicines: 三七”)

J Ethnopharmacol 2009;125:380


Radix et rhizoma notoginseng sanqi4
Radix et Rhizoma Notoginseng(sanqi, “ traditional Chinese herbal medicines: 三七”)

J Ethnopharmacol 2009;125:380


Radix et rhizoma notoginseng sanqi5
Radix et Rhizoma Notoginseng(sanqi, “ traditional Chinese herbal medicines: 三七”)

J Ethnopharmacol 2009;125:380


Kfj ng may 2011

  • Get to know the traditional Chinese herbal medicines: “bad guys”

  • Know the common ones used in your locality

  • Back to the basics

  • Haemostasis testing


Can you tell me
Can you tell me… traditional Chinese herbal medicines:

  • Indication for treatment?

  • Drug interactions?

  • Precautions e.g. menstruation?

  • Bleeding symptoms


Kfj ng may 2011

Printer traditional Chinese herbal medicines:

LCD screen

Soft keys

Trigger solution

Test

cartridge

Cassette

Carousel


Kfj ng may 2011

EPICT = 188 sec traditional Chinese herbal medicines:

Sensitivity = 88%

Specificity = 52%


Thank you

Thank You traditional Chinese herbal medicines: