Cell Theory and Structure. Development of the Light Microscope Evolution of the Cell Theory Spontaneous Generation Disproven Histochemistry , Mitosis, and Meiosis Classes of Biochemicals in Cells Electron Microscopy and Ultrastructure. The Microscope.
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Galileo’s first microscope from 1609
Illustrations of honey bees made with an improved Galileo microscope in 1630
Made a powerful single-lens microscope with which he observed many types of unicells and tissues. He even drew bacteria.
A single-lens microscope
His drawing of an ash stem section
Much of the microscopic work of the rest of the 17th and 18th centuries was descriptive [and there was much to describe].
Trunnion Model microscope made by Charles A. Spencer (1813-1881), US manufacturer of microscopes
Virchow’s cell theory
The use of aniline dye to stain white blood cells
Published in 1882
Max Knoll (1897-1969, Germany, left) and Ernst Ruska (1906-1988, Germany, right) with first TEM
Vladimir Kosmich Zworykin (1888-1982, Russia and USA) invented SEM and television (both based on raster principle)
With early television (kinetoscope) in 1929
Flagellum or Cilium