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New tissue acquisition tools for gene expression analysis. Tissue quality and patient comfort. Prof. Jaak Ph. Janssens MD, PhD. Translational Research. Molecular biology research PCR, microchips, Proteomics, genomics,… Mutation research, polymorphisms Screening Risk biomarkers

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new tissue acquisition tools for gene expression analysis

New tissue acquisition tools for gene expression analysis

Tissue quality and patient comfort

Prof. Jaak Ph. Janssens MD, PhD

translational research
Translational Research
  • Molecular biology research
    • PCR, microchips,
    • Proteomics, genomics,…
    • Mutation research, polymorphisms
  • Screening
    • Risk biomarkers
  • Diagnosis
    • Fine tuning and reclassification
  • Personalized therapy
    • Prognostic markers
    • Pathway analysis – response prediction
requirements for tissue acquistion related to translational research
Requirements for tissue acquistion related to translational research
  • Tissue quality
    • Representative
    • One large piece of tissue
    • No artifacts
  • Patient comfort
    • No pain, no complication risk = safe
  • Inexpensive
  • Access
    • Handsome
    • Fast – minimal personnel
    • No dedicated room
slide7

Fine needle aspiration (Cytology)

  • Microbiopsy (16 to 14 Gauge)
  • Macrobiopsy (8 to 12 Gauge)
  • Open biopsy (general anaesthesia)
slide16

Medinvents’ Products

  • A range of large core soft tissue biopsy needles
  • Based on NEW double rota-cutting technique
  • 8 – 14 Gauge
  • Vacuum system on Single Use
  • Product portfolio:
    • Spirotome Single Use/Reusable
    • Spirotome Cervicore ™
    • Spirotome MRI ™
    • Spirotome Bone ™
    • Spirotome Easy Punch ™
  • Automated version
  • Handheld or stereotactically positioned
  • Reusable handle controller, disposable
  • 8 – 10 Gauge needles
  • Vacuum assisted system
  • Multiple samples without reinserting
slide17

Medinvents’ Applications

  • Spirotome™
  • Breast
  • Thyroid
  • Salivary glands
  • Thoracic wall
  • Abdominal wall
  • Lymph nodes
  • Muscle
  • Liver
  • Coramate ™
  • Breast
  • Thyroid
  • Salivary glands
  • Thoracic wall
  • Abdominal wall
  • Lymph nodes
  • Muscle
  • Spirotome Cervicore ™
  • Cervix
  • Uterus
  • Spirotome Bone ™
  • Soft tissues within bone
  • Spirotome Easy Punch ™
  • Skin
  • Vulva