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Log (sec)

Log (sec)

Log (sec)

Log (sec)

Log (sec)

Log (sec)

Log (sec)

Supplementary Figure 2: Deuterium uptake in selected segments of PGC-1α 220 at pH 6.0 and pH 7.5. All time points are converted to pH 7.5 using equation 1 (also see table 1). All build up curves show overlap within the experimental errors indicating the unchanged dynamics of apo PGC-1α 220 at pH 6.0 and 7.5.