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Emmanuel Acha ASONGALEM Vice Dean, Research and Cooperation , Faculty of Health Sciences University of Buea Email : cpehw@yahoo.com, emmanuel.asongalem@ubuea.net Tel: 237 7554 5718. THE STATE OF BIOMEDICAL RESEARCH IN CAMEROON. Objectives. Introduction

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the state of biomedical research in cameroon

Emmanuel Acha ASONGALEM

Vice Dean, Research and Cooperation,

Faculty of Health Sciences

University of Buea

Email: cpehw@yahoo.com, emmanuel.asongalem@ubuea.net

Tel: 237 7554 5718

THE STATE OF BIOMEDICAL RESEARCH IN CAMEROON

objectives
Objectives
  • Introduction
  • Organisation of research in Cameroon
  • Biomedical Research Centres
  • National biomedical research priorities
  • Percentage distribution of research conducted in Cameroon
  • Types of research
  • Research funding
  • Some ongoing clinical researches going on in Cameroon
  • Some biomedical researches going on in UB
  • Unethical incidence of biomedical research
  • Ethical issues in Cameroon
  • Areas of collaboration

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cameroon
Cameroon

Official Name: Republic of Cameroon Area: Capital: Yaounde

Official Languages

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organisation of research in cameroon
Organisation of research in Cameroon
  • No single National organisresponsible for coordinatingresearch in Cameroon.
  • ThreeMinistries are involve in biomedicalresearch:
    • MinistryHigher Education (MINESUP)
      • Coordinated by Div. OperationalResearch
    • Ministry of Health (MINSANTE)
      • Coordinated by Division of OperationalHealthResearch
    • Ministry of ScientificResearch (MINRESI)
      • Coordinated by Div. of Research and Program Policy)

BiomedicalConference - Kumasi, 2012

centers of biomedical research
Centers of BiomedicalResearch
  • MINISTRY OF SCIENTIFIC RESEARCH
    • Camdiagnostics
    • Institute of MedicalResearch and Medicinal Plants Studies (IMPM)
    • National Institute for Agricultural Research (IRAD)
  • MINISTRY OF HIGHER EDUCATION
    • Universities (8 state and >10 private)
      • University of Buea – Malaria, HIV/AIDS, Influenza virus and otheremerginginfectiousdiseases
      • University of Yaounde 1 – Malaria, HIV/AIDS, Metabolic syndrome
      • University of Douala – Malaria
      • University of Dschang – Malaria
  • MINISTRY OF HEALTH
    • International Reference Center of Chantal Biya (IRCCB)
    • Institute Pasteur – Medical Services
    • Organization of Coordination for the fight against endemic diseases in Central Africa (OCEAC) – Malaria, HIV/AIDS, infectiousdiseases
    • PRESICA, Yaounde – HIV/AIDS
    • InvestigativeResearch – Cameroon (IRECAM) – HIV/AIDS
    • Baptist Center, Mutengene – HIV/AIDS
    • National HealthLaboratory (Hygiene Mobile) – emergingdiseases
    • National Laboratory for quality control of drugs (CENAME) – National Medication Distribution Center.

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national biomedical research priorities
National Biomedicalresearchpriorities

BiomedicalConference - Kumasi, 2012

distribution of health research in cameroon
Distribution of Health Research in Cameroon

BiomedicalConference - Kumasi, 2012

types of biomedical research in cameroon
Types of biomedical research in Cameroon

Biomedical Conference - Kumasi, 2012

preclinical research
Preclinical research

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study types of clinical trials
Study types of Clinical Trials

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distribution of primary outcomes of clinical trial performed in cameroon
Distribution of primary outcomes of clinical trial performed in Cameroon

Biomedical Conference - Kumasi, 2012

sources of biomedical research sponsorship
Sources of biomedical research sponsorship

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budget estimates for research in cameroon
Budget estimates for research in Cameroon

* Not specifically for biomedical research

† subsidises to public medical schools and research institution; excludes money in collaborative centers such CIRCB

‡ allocated for health research . It is mainly given to IMPM

NA: data not available

§ Allocation from Global fund to fight HIV/AIDS, Malaria and TB

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areas of international sponsored research
Areas of international-sponsoredresearch

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distribution of sponsorship
Distribution of sponsorship

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sponsors of biomedical reseach in cameroon
Sponsors of Biomedicalreseach in Cameroon
    • International organs
      • WHO (TDR, UNAIDs, Global Fund)
      • European Union (EDCTP project on HIV/AIDS, Malaria, TB, CANTAM)
      • United Nations Family Planning Agency (UNFPA)
      • UNICEF
      • World Bank (Global Fund for the fightagainst HIV/AIDS/TB/Malaria)
      • GTZ
    • International NGOs
      • Helen Keller International
      • Gates & Melinda Foundation
      • Médecins Sans Frontiére
    • Pharmaceutical companies
      • Pfizer
      • Sanofi Aventis
      • Gilead Science
      • Roche
  • National institutions
    • Government (Universities, IMPM, CENAME, Hygiene Mobile)
    • Private (verylittle contributions)
  • International sponsors & Institutions
    • America
      • Centre for Disease Control
      • John Hopkins School of Public Health
      • National Institutes of Health
      • US Army HIV Researchproject (LEID)
      • USAID
    • France
      • Institut de Recherche pour la Développement (IRD)
      • French National Agency for Research on AIDS and Viral Hepatitis (ANRS, France)
      • Centre de Recherche pour la Santé des Armées (CRESAR)
    • Italy
      • CIRCB
    • Canada
      • Canadian International DevelopmentResearch Center (IDRC)

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clinical trials going on in cameroon
Clinical trials going on in Cameroon

BiomedicalConference - Kumasi, 2012

some biomedical researches going on in ub
Some biomedical researches going on in UB

BiomedicalConference - Kumasi, 2012

unethical incidence of biomedical research
Unethical incidence of biomedical research
  • Tenofovir (VIREAD) prophylactic or preventive properties against HIV infection
    • Cambodia and West Africa (Cameroon, Ghana & Nigeria) (started July, 2004).
    • Gates Foundation (USA)  Family Health International (FHI –USA)  Care and Health Programme (CHP) – an NGO.400 uninfected sex workers (200 test drug + 200 placebo)
  • Visit by Act Up-Paris and REDS (Réseau Ethique Droit et Santé, to Cameroon, protest from sex workers, picked up by France-2 TV, magnified and trial suspended in February 2005.
  • Causes leading to failure
    • Transport of USD3
    • Prevention package did not include female condoms
    • 5 social workers to counsel 100 participants
    • Infected HIV participants were not to treated with HIV drugs
    • 6 (palcebo) 4 (Tenofovir) have seroconverted by August 2005.
    • State-of –the-art treatment was ordered by FHI.

BiomedicalConference - Kumasi, 2012

ethical issues in cameroon
Ethical issues in Cameroon
  • All health research projects must obtain permits from the Div. of Operational Research in MPH.
    • About 14 ERCs in Cameroon, but only 2 are recognized at the MPH (the national ERC (1987), and the ethics committee of Centre International de Reference Chantal Biya (CIRCB) since 2006)
    • To date, Administrative Authorization for clinical trials and protocols with international collaboration is only granted for protocols reviewed at the National Ethics Committee
    • The MPH (in collaboration with the CNEC) is currently proposing a guide to regulate the creation of Institutional Review Boards in Cameroon
    • Faculty of Health Sciences, University of Buea, has a functional ERB for both students and externally funded projects

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areas of collaboration with university of buea
Areas of collaboration with University of Buea

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conclusion
Conclusion

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references information sources
References & Information sources
  • National Ethical Committee of Cameroon, Yaounde.
  • Ministry of Health
    • Division of operational Health research
      • http://dev.cdnss.dros-minsante-cameroun.org/
  • Ministry of Higher Education
    • Division of Operational research
      • http://www.citi.cm/minesup-recherche/
  • Ministry of Scientific Research & Innovation
    • Division of Rsearch and Program Policy
      • http://www.minresi.net/minresi/
  • Cadre de dépenses à Moyen Terme Santé by Ministry of Public Health, 2010
  • Situational Analysis of Health Research in Cameroon by Council on Health Research for Development (COHRED), 1995.
  • Libraries and interviews
    • University of Buea
    • University of Yaounde1
    • University of Douala
    • Univesity of Dschang
  • OCEAC library
  • Global fund (www.theglobalfund.org)

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