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High Frequency Variability of Heart Rate

High Frequency Variability of Heart Rate. Baroreceptor. Brain stem. 2. V. 1. 3. Arterial Pressure. Lung Volume. SA node. Physiology of Respiratory Sinus Arrhythmia. Output - Vagus nerve Input - Pulmonary stretch receptor. Vagal Tone Dependent. Anrep , 1936.

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High Frequency Variability of Heart Rate

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  1. High Frequency Variability of Heart Rate Baroreceptor Brain stem 2 V 1 3 Arterial Pressure Lung Volume SA node

  2. Physiology of Respiratory Sinus Arrhythmia • Output - Vagus nerve • Input - Pulmonary stretch receptor

  3. Vagal Tone Dependent • Anrep , 1936

  4. Lung Volume Dependent • Anrep, 1936

  5. Response to Change in Lung Volume • Anrep, 1936

  6. Linear to Vagal Tone • Anrep, 1936

  7. Influences of Sympathetic and Parasympathetic nerves • Anrep, 1936

  8. Physiology of Respiratory Sinus Arrhythmia • Output - Vagus nerve • Input - Baroreceptor

  9. HFRR and Baroreflex • Fundamental relations between short-term RR interval and arterial pressure oscillations in humans. Circulation (1996)

  10. Respiratory sinus arrhythmia as a measure of parasympathetic cardiac control • Fouad et al, 1984 Fig 1-5 • Pomeranz, 1985

  11. HFRR and Sympathetic or Vagal nerves • Effect of cardiac vagal and sympathetic nerve activity on heart rate in rhythmic fluctuations. J. Auton. Nerv. Sys. (1985)

  12. How Vagal Activity Affects HRV • Berger et al., 1989 (Fig 1, 4)

  13. Limitations

  14. HFRR and Intrinsic Mechanism • Evidence for an intrinsic mechanism regulating heart rate variability in the transplanted and the intact heart during submaximal dynamic exercise?Cardiovasc. Res. (1990) • Is respiratory sinus arrhythmia a good index of cardiac vagal tone in exercise ?J. Appl. Physiol. (1996)

  15. High Frequency Variability of Heart Rate Baroreceptor Brain stem 2 V 1 3 Arterial Pressure Lung Volume SA node 1.Baroreflex dependent pathway (tilt) 2.Baroreflex independent pathway (supine) 3.Non-autonomic pathway (cardiac denervation)

  16. Low Frequency Variability of Heart Rate Central oscillator 2 Brain stem Sy V 1 Baroreceptor SA node 1.Baroreflex dependent pathway (major) 2.Baroreflex independent pathway (minor)

  17. Spectral analysis of fluctuations in cardiovascular parameters: a quantitative tool for the investigation of autonomic control---詹婉卿 Respiratory sinus arrhythmia: noninvasive measure of parasympathetic cardiac control---王春惠 Evidence for an intrinsic mechanism regulating heart rate variability in the transplanted and the intact heart during submaximal dynamic exercise?---賴賢勇 Spectral analysis of blood pressure and heart rate in conscious rats: effects of autonomic blockers---劉信宏

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