ap biology n.
Download
Skip this Video
Loading SlideShow in 5 Seconds..
AP Biology PowerPoint Presentation
Download Presentation
AP Biology

Loading in 2 Seconds...

play fullscreen
1 / 11

AP Biology - PowerPoint PPT Presentation


  • 124 Views
  • Uploaded on

AP Biology. Chapter 12: The Cell Cycle. Checkpoints (Is all going according to plan?). G 1. S. G 2. G 1. M. M. M. S. G 2. MPF activity. Cyclin. Relative concentration. Time. Fluctuation of MPF activity and cyclin concentration during the cell cycle. G 1. Cyclin. S. Cdk. M.

loader
I am the owner, or an agent authorized to act on behalf of the owner, of the copyrighted work described.
capcha
Download Presentation

PowerPoint Slideshow about 'AP Biology' - bryony


An Image/Link below is provided (as is) to download presentation

Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.


- - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - -
Presentation Transcript
ap biology

AP Biology

Chapter 12:

The Cell Cycle

slide3

G1

S

G2

G1

M

M

M

S

G2

MPF activity

.

Cyclin

Relative concentration

Time

Fluctuation of MPF activity and cyclin concentration

during the cell cycle

slide4

.

G1

Cyclin

S

Cdk

M

Degraded

cyclin

G2

accumulation

G2

checkpoint

Cdk

Cyclin is

degraded

Cyclin

MPF

Molecular mechanisms that help regulate the cell cycle

slide5

Chromosome

movement

.

Kinetochore

Tubulin

subunits

Motor

protein

Microtubule

Chromosome

slide6

Cells anchor to dish surface and

divide (anchorage dependence).

When cells have formed a complete

single layer, they stop dividing

(density-dependent inhibition).

.

If some cells are scraped away, the

remaining cells divide to fill the gap and

then stop (density-dependent inhibition).

25 µm

Normal mammalian cells

slide7

Cancer cells do not exhibit

anchorage dependence

or density-dependent inhibition.

.

25 µm

Cancer cells

mutations and cancer

MUTATION

Growth

factor

Hyperactive

Ras protein

(product of

oncogene)

issues signals

on its own

G protein

Cell cycle-stimulating

pathway

Protein kinases

(phosphorylation

cascade)

Receptor

NUCLEUS

Mutations and Cancer

Transcription

factor (activator)

DNA

Gene expression

Protein that

stimulates

the cell cycle

Cell cycle-inhibiting

pathway

Protein kinases

MUTATION

Defective or

missing

transcription

factor, such as

p53, cannot

activate

transcription

Active

form

of p53

UV

light

DNA damage

in genome

DNA

Protein that

inhibits

the cell cycle

slide10

Question: Lectins are naturally occurring plant proteins that help promote increased mitosis within plant root tips. These proteins influence the normal production of MPF within the root cells and thereby speed up the cell cycle. In no more than three sentences, state ONE similarity and TWO differences between Lectin influenced cells and cancer cells. (5 Points)

slide11

Scoring Rubric: 1pt. Discussion of one similiarity

  • Possible discussion points: Increased cell cycle rate.
  • Cyclin production rate is altered.
  • 1pt. Discussion of difference number 1
  • 1pt. Discussion of difference number 2
  • Possible discussion points: Cancer does not respond to checkpoints.
  • Cancer does not have density dependent.
  • Cancer does not have anchorage dependence.
  • Cancer not normal function for cells.
  • Cancer affects normal cyclin production.
  • Cancer being caused by carcinogens, etc.
  • 1pt. Correct use of scientific terms.
  • 1pt. Answer has no more than three sentences. (Following Directions.)
  • This question addresses Essential Knowledge: 2.D.3