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The Price of Survival Acute Lymphocytic (ALL) Leukemia in Children. By Hailey Taylor English 252. What is Acute Lymphocytic Leukemia?. cancer of the white blood cells -- the cells in the body that normally fight infections (“ Acute Lymphoblastic Leukemia in Children” par 1).

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what is acute lymphocytic leukemia
What is Acute Lymphocytic Leukemia?
  • cancer of the white blood cells -- the cells in the body that normally fight infections

(“Acute Lymphoblastic Leukemia in Children” par 1)

there are two main types of white blood cells 1 lymphoid cells 2 myeloid cells
There are two main types ofwhite blood cells:1. lymphoid cells 2. myeloid cells

(“Acute Lymphoblastic Leukemia in Children” par 1)

slide4

ALL leukemia affects lymphoid cells

(“Childhood Acute Lymphoblastic Leukemia Treatment”)

slide5

For Example…

When eighteen month old Rylee was diagnosed with acute lymphocytic leukemia…

  • Her white blood cell count was high
  • Her red blood cell count was way low (hers was at a 12, normal is 35)
  • Her platelets were also low
slide6

When Leukemia is diagnosed…

  • There are usually about 100 billion leukemia cells in the body
  • Killing 99.9% of these leukemia cells during the 1-month induction treatment is enough to achieve a remission
  • But it still leaves about 100
  • million leukemia cells
  • in the body

(“Detailed Guide: Leukemia Children’s Treatment of Children with Acute Lymphocytic Leukemia” par 2)

slide7

Treatments:

  • Treatments have come a long way since the 1960s
  • A child diagnosed with ALL leukemia then had
  • a very low chance of survival
  • Now, in most cases it is 85%
  • curable
  • (“Childhood Cancer Survivors Coached to Improve Learning Disabilities” par 7).
slide8

Treatments/Effects:

Chemotherapy &

Radiation

slide9

Treatment Effects:

“While radiation and chemotherapy save young lives . . . at least 100 research studies have concluded that radiation therapy (not chemotherapy) directed at a still-developing brain, can impair thinking, attention, memory, speech, and flexible thought”

-Robert W. Butler, PhD, clinical psychologist at

Doernbecher Children’s Hospital and associate

professor of pediatrics at Oregon Health and

Science University in Portland

(“Childhood Cancer Survivors Coached to Improve Learning Disabilities” par 8)

slide10

Treatment Effects:

“We’ve been aware of learning disabilities as a side effect for a couple of decades, and we’ve all been very frustrated by it . . . But you have to take the choice of whether you want the child to survive. Most people choose the learning disability, especially if we are able to alter the outcome by giving special learning classes to the children”

-Donna Copeland, PhD, a professor of pediatrics at University of Texas

Medical School, M.D. Anderson Cancer Center

(“Childhood Cancer Survivors Coached to Improve Learning Disabilities” par 10).

slide11

“If we rejected doing chemo, cancer could overtake her body, spine, central nervous system or brain. If we stick to traditional treatment, the chemo can and most likely will have at least some lasting negative effects. Will Rylee beat all the odds? I guess we'll take our chances” (Taylor, Natalie).

slide12

Looking up…

The Leukemia & Lymphoma Society:

“Most survivors of childhood leukemia or lymphoma do not develop significant long-term or late effects of treatment. Effects can range from mild to severe . . . It is important for parents to discuss possible long-term and late effects with their child’s treatment team so that the

proper planning, evaluation and

follow-up can take place”

(“Long-Term and Late Effects of Treatment for Childhood Leukemia or Lymphoma” 2)

slide13

Works Cited

  • “Acute Lymphoblastic Leukemia in Children.” National Cancer Institute. 11 July 2002. 1 March
  • 2009 <http://www.cancer.gov/cancertopics/factsheet/ALLinchildren>.
  • “Acute Lymphocytic Leukemia: Understanding ALL.” The Leukemia & Lymphoma Society
  • Fighting Blood Cancers. 14 July 2008. 1 March 2009 < http://www.leukemia-lymphoma
  • .org/all_page.adp?item_id=7049>.
  • “Childhood Acute Lymphoblastic Leukemia Treatment.”National Cancer Institute, National
  • Institutes of Health.14 Feb. 2008. 5 March 2009 < http://www.medem.com/medlib/article/
  • ZZZHE608L0E>.

“Childhood Cancer Survivors Coached to Improve Learning Disabilities.” ACS News Center. 11

Feb. 2001. 17 Feb. 2009 <http://www.cancer.org/docroot/NWS/content/NWS_1_1x_

Childhood_Cancer_Survivors_Coached_to_Improve_Learning_Disabilities.asp>.

“Detailed Guide: Leukemia - Children’s Treatment of Children with Acute Lymphocytic

Leukemia.” American Cancer Society. 19 August 2007. 1 March 2009 <http://www.

cancer.org/docroot/CRI/content/CRI_2_4_4X_Treatment_of_Children_with_Acute_Lym

phocytic_Leukemia_24.asp>.

“Late Effects of Treatment for Childhood Cancer: Treatment - Patient Information.” National

Cancer Institute. 1 July 2008. 23 Feb. 2008 < http://www.everettclinic.com/kbase/

nci/ncicdr0000373791.htm>.

“Long-Term and Late Effects of Treatment for Childhood Leukemia or Lymphoma.” The

Leukemia & Lymphoma Society Fighting Blood Cancers. 17 February 2009 < http://

www.leukemia-lymphoma.org/attachments/National/br_1193318745.pdf>.

Taylor, Natalie. Personal Interview. 28 Feb. 2009.

Taylor, Rylee. Personal Photograph by Natalie Taylor.