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Introduction to Bruker Optics, NSC Mid Year Sales Meeting Sept 2007, By Muhammad Saeed

Introduction to Bruker Optics, NSC Mid Year Sales Meeting Sept 2007, By Muhammad Saeed. offers the complete product line is leading in technology and innovations is steadily growing is the only European supplier is world wide present. Bruker Optics.

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Introduction to Bruker Optics, NSC Mid Year Sales Meeting Sept 2007, By Muhammad Saeed

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  1. Introduction to Bruker Optics, NSC Mid Year Sales Meeting Sept 2007, By Muhammad Saeed

  2. offers the complete product line is leading in technology and innovations is steadily growing is the only European supplier is world wide present Bruker Optics

  3. FT-IR FT-NIR Raman Terahertz TD-NMR • Our products are based on • molecular spectroscopy

  4. Bruker Group Founded in 1960 in Germany Bruker world wide today : > 3000 Employees > 25 Locations > 50 Sales and Service Offices > 700 Mio. $ Revenue

  5. Bruker Group Company Technology X - Ray Fluorescence and Diffraction Mass Spectrometry NMR-Spectrometry Optical Spectroscopy

  6. Bruker Optics - we offer solutions Process Monitoring Laboratory Analysis Research & Development Life Science Academics Quality Control

  7. Bruker Optics product line • Bruker is the only supplier with a complete product line TENSOR 27/37 FT-IR Spectrometer VERTEX 70/80 FT-IR Spectrometer IFS 125 FT-IR Spectrometer ALPHA FT-IR Spectrometer 1.) Basic IR up to highest resolution spectrometer. World record: The IFS 125 HR is the spectrometer with the highest resolution in the market World record: The Alpha is world’s smallest FTIR Spectrometer.

  8. Bruker Optics product line • Bruker is the only supplier with a complete product line HELIOS HYPERION Imaging 2.) Microscopy -Sample compartment microscope -IR microscope -IR imaging microscope -Raman microscope

  9. Bruker Optics product line • Bruker is the only supplier with a complete product line MPA MATRIX Industry 3.) Near IR spectrometer -Lab QA/QC -Process

  10. Bruker Optics product line • Bruker is the only supplier with a complete product line RAM II RFS 100 SENTINEL 4.) Complete Raman product line FT-Raman module FT-Raman spectrometer Dispersive Raman process Dispersive Raman microscope

  11. Bruker Optics product line • Bruker is the only supplier with a complete product line Spectrographs minispec TeraView 5.) Plus Minispec TeraHertz Spectrographs

  12. Bruker Optics product line • Bruker is the only supplier with a complete product line PAT Food Polymer 6.) Solutions for dedicated markets: - Process

  13. Bruker Optics product line • Bruker is the only supplier with a complete product line Proteomics Microbiology Tissue 6.) Solutions for dedicated markets: - Life Science

  14. Introduction to FT-IR spectroscopy

  15. Discovery of infrared light In the year 1800 the astronomer Friedrich Wilhelm Herschel analyzed the spectrum of sunlight. Herschel created the spectrum by directing sunlight through a glass prism so that the light was divided into its different colors. He measured the heating ability of each color using thermometers with blackened bulbs. When he measured the temperature just beyond the red part of the spectrum he noticed some kind of invisible radiation. Much to his surprise he found that the area close to the red part (i.e. an area apparently devoid of sunlight) had the highest heating ability of all. Herschel concluded that there must be a different kind of light beyond the red portion of the spectrum, which is not visible to the human eye. This kind of light became known as “infrared” (below red) light. Herschel then placed a water-filled container between the prism and thermometer and observed that the temperature measured was lower than the one measured without the water. Consequently, the water must partially absorb the radiation. In addition, Herschel could prove that depending on how the prism was rotated (i.e. depending on the spectral range) the difference in the temperatures measured for each color varied. This was the beginning of infrared spectroscopy. Infrared spectroscopy measures the infrared light that is absorbed by a substance. This absorption depends on the wavelength of the light. Friedrich Wilhelm Herschel (1738 - 1822)

  16. ~ ~   The electromagnetic spectrum The electromagnetic spectrum Visible light and infrared light are two types of electromagnetic radiation, but with different wavelengths, or frequencies. In general, electromagnetic radiation is defined by the wavelength  or the linear frequency . The wavelength is the distance between two maxima on a sinusoidal wave. The frequency is the number of wavelengths per unit time. Since all electromagnetic waves travel at the speed of light, the frequency corresponding to a given wavelength can be calculated as:  = c/ According to the Plank’s Radiation Law, the frequency of electromagnetic radiation is proportional to its energy. E = h• In infrared spectroscopy wavenumber is used to describe the electromagnetic radiation. Wavenumber is the number of wavelengths per unit distance. For a wavelength  in microns, the wavenumber, , in cm-1, is given by = 10000/ Sinusoidal wave of wavelength 

  17. The electromagnetic spectrum The electromagnetic spectrum The electromagnetic spectrum

  18. Matter Photoluminescence Transmission Reflection Scattering Interaction of radiation and matter Interaction of radiation and matter If matter is exposed to electromagnetic radiation, e.g. infrared light, the radiation can be absorbed, transmitted, reflected, scattered or undergophotoluminescence.Photoluminescence is a term used to designate a number of effects, including fluorescence, phosphorescence, and Raman scattering. Incident light beam Absorption

  19. Separation of spectral ranges NIR MIR FIR 15,000 cm-1 4,000 cm-1 400 cm-1 5 cm-1

  20. The working principle of an FT-IR spectrometer Infrared light emitted from a source (e.g. a SiC glower) is directed into an interferometer, which modulates the light. After the interferometer the light passes through the sample compartment (and also the sample) and is then focused onto the detector. The signal measured by the detector is called the interferogram. General FT-IR spectrometer layout

  21. FT-NIR Spectrometer MPA - Multi Purpose Analyzer

  22. FT-NIR Spectrometer MATRIX-I: Process Analysis in Diffuse Reflection

  23. NIR Spectroscopy in the Food Industry Qualification of Raw Materials • Disinfecting Materials • Detergents • Aromas • Milk Powder (liquid Milk) • Thickening Agents • Starches • ....

  24. NIR Spectroscopy in the Food Industry Quantification of Ingredients • Sugar Content in Water/juices • Pure Yolk/Alcohol Content inEgg Liquor • Moisture Content/Total Sugar in Marzipan • Fat/Protein/Water/Mineral Salt in Sausages • Fat/Water/Protein/sugar in Mayonnaise or in Chocolate • Fat/Dry Matter in Ice Cream • Caffeine in Black Tea • Caffeine in Instant Coffee • Bloom-Number in Gelatine • Trans Fatty Acids in Edible Oils (MIR) • Moisture/Protein/Starch/Ash/Raw Fiber in Cereals • Moisture/Nicotine in Tobacco • ....

  25. NIR IN Polymer Chemistry Applications • Additives (Antioxidants, Lubricants, Modifiers, ...) • Filler • physical Properties (Density, Viscosity, ...) • averaged Molecular Weight • MFI (Melt Flow Index) • Humidity • Content of Carboxyl End Groups • OH-Number • Acid Number • Monomer Content • ...

  26. NIR in Polymer Chemistry • Stabilizer Content • Content of Rest Monomer • Density • Viscosity • MIBK (Methyl-Isobutyl-Ketone) • WPE (Weight per Epoxy) • MBCI (Poly(Etherurethane)Diisocyanate) • Content of Total PE, PEP, PEEP and Block-Co-Polymer • ...

  27. NIR Applications In Petrochemistry • Octane Number (RON & MON) • Flash Point • Cloud Point • Boiling Behavior • Cooling Behavior • Content of Aromates • ...

  28. NIR Applications of Pharmaceuticals • Identification in the Receipt of Goods • Quantification of • active Materials • auxiliary Materials • Filler • in Powders, Capsules, Tablets or Phials • Water Content in Powders • Surveillance of Drying Processes • Mixing • Solvent Recovery • Placebo/Verum Studies • Wall Thickness of Capsules • physical Properties (Hardness, Brittleness, … )

  29. NIR Application in Feed and Feed ingredients The Feed and Feed Ingredients calibrations include feed for various animals like ruminant, poultry, swine, horse and fish, as well as feed ingredients like seeds, cereals, legumes, roughage and animal by-products.

  30. NIR (MPA) Advantages Advantages • Fast (10 - 20 sec. typical) • No sample preparation, simple to operate • No waste, no pollution • Simultaneous determination of multiple components per measurement • Highly precise and accurate • Measure through packaging • Transferable methods • Real time monitoring for process NIR

  31. Summary • Very often the time consumption for the method development is for HPLC and GC higher than NIR • The NIR analysis time is generally much faster. • Mostly installation and maintenance-costs for in-line- & off-line application is much lower for NIR. • NIR = cost effective!

  32. Competition

  33. Competition FOSS = giant Founded in 1956, >50 years exper. 1100 employees for Agri applications worldwide, 300 service & appl. staff Present in 21 countries Perfect marketing and market knowledge 100++ distributors Created “agri” standards

  34. Competition • FOSS: • 6500/5000 will die in 2007 • Still problems with InfraXact • Old fashioned XDS is promoted: • „XDS is the latest & outstanding technology. In the past only the high priced Pharma customers have had access. Now it is available for everybody.“ • FOSS is getting more aggressive also in pricing • FOSS is in trouble – use it now!

  35. Competition THERMO: Currently very active! Focus on Pharma/PAT Attacks classical BRUKER markets (non-agri) Still relatively weak in NIR, but THERMO is a “sleeping shark”

  36. Competition • THERMO Strategy: • Offering full options at low price • Engineering is weak • Our answer: • You need to know our USPs adapted to the customers needs • Demonstrate the value of MPA for the dedicated customer application • NIR: Quality beats price!

  37. Competition • BÜCHI: • Focus on Agri and Grain • Cross selling • Active in limited number of countries (now +US) • ABB: • Focus on Process and Dairy • Strong in Petro & all kind of OEMs

  38. Strategy for the Key Markets

  39. Strategy for Chemistry Applications • Endless number of applications are possible: OH, acid number, QA/QC, in-line & off-line • High benefits of NIR by replacing HPLC • MPA = blockbuster • Our sales structure fits perfectly to this market (solving applications on site) • Bio fuels are coming!

  40. Strategy for Polymer Applications • Most Key Accounts are still OPEN like SABIC. • Biggest margins could be earn by developing applications.

  41. Strategy for Pharma Applications • All world’s biggest companies are using Bruker’s MPA. • Pharma could be best future prospective. • Applications: • STILL: raw ID & tablet testing (by MPA)

  42. Strategy for PetroChemistry Applications • Saudi ARAMCO could be big customer and we can make good margin. • Need to work very closly. • NSC already involved and have done applications.

  43. Strategy for F & F (Food & Agri) Applications • The market still OPEN. • Big Companies(Provimi, Degussa, Addiseo, Nestlé, …) now using Bruker’s systems which could be useful for F&F business in KSA. • The Dairy Companies still using old techniques which is good news for us. • Markets are ready for us. We are highly welcome!!

  44. To Do List • Bruker = Market Leader • We create the standards • (in non-agri) • Others will copy our success: • Save your market shares • Diversify – put not all eggs in one basket

  45. To Do List • Put more efforts in the chemical market • Promote INGOT • Communicate (via M.Saeed) – Knowledge & expertise is getting more and more important • Do not hesitate to ask for support

  46. One final remark about the future SM

  47. Thank you very much! www.brukeroptics.com

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