1 / 1

Collaborators

OpenFlyData Integration of Drosophila gene expression image data Alistair Miles, Jun Zhao, Graham Klyne and David Shotton e-mail: firstname.lastname@zoo.ox.ac.uk Image Bioinformatics Research Group, Department of Zoology, University of Oxford. Summary

braima
Download Presentation

Collaborators

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. OpenFlyData Integration of Drosophila gene expression image data Alistair Miles, Jun Zhao, Graham Klyneand David Shotton e-mail: firstname.lastname@zoo.ox.ac.uk Image Bioinformatics Research Group, Department of Zoology, University of Oxford • Summary • Bioinformatics databases are characterized by the heterogeneity of their user interfaces, content and data models, frustrating efforts to achieve cross-resource data integration. • Images of gene expression locations, obtained by mRNA in situ hybridization, are vital to our understanding of development. • OpenFlyData (http://www.openflydata.org) is an open source demonstration data web that uses lightweight Semantic Web technologies to integrates information from four Drosophila gene expression databases on the fly into a single Web browser window. Data sources BDGP (http://www.fruitfly.org/cgi-bin/ex/insitu.pl) and FlyTED (http://www.fly-ted.org/) are databases of gene expression images from Drosophila melanogaster embryos and adult testes, respectively. FlyAtlas (http://www.flyatlas.org/)holds quantitative data on mRNA expression levels obtained from Affimetrix DNA chips. FlyBase (http://flybase.org/) is the global database of Drosophila genetic information, providing name disambiguation and references. Despite their heterogeneity, they can all be integrated by OpenFlyData Figure 1: The BDGP Drosophilaembryo gene expression image database Figure 2: The FlyTED Drosophila testis gene expression image database Figure 3: The FlyAtlas database of quantitative Drosophila gene expression data Figure 4: FlyBase, the global database of Drosophila genetic information Data from these four sources integrated in a single OpenFlyData window • Funding acknowledgements • FlyTED: BBSRC Systems Biology Committee BB/C503903/1. • FlyData: BBSRC Tools and Resources Fund BB/E018068/1. • Defining Image Access (a data web requirements analysis project): JISC Repositories and Preservation Programme. • FlyWeb: a Data Web for Drosophila Research: JISC Integrated Information Environment Committee. • Collaborators

More Related