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Random walk through NIH grants. Yi Wang @ Cornell BME Surgery retreat 08. Why do you want to do NIH grant?. Money, more money Everyone is doing it May be the best review process Transparent/fair, iterative …. All you want to know are readily available at your finger tips!. www.nih.gov
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Random walk through NIH grants Yi Wang @ Cornell BME Surgery retreat 08
Why do you want to do NIH grant? • Money, more money • Everyone is doing it • May be the best review process • Transparent/fair, iterative • …
All you want to know are readily available at your finger tips! www.nih.gov http://grants.nih.gov/grants/oer.htm
NIH: Myths, realities… 55% basic research; 45% applied research; 5% other 92% unsolicited (investigator initiated); 8% solicited 20% success rate http://grants.nih.gov/grants/peer/prac/prac_may_2006/zerhouni_crossroads.ppt#407,1,Slide 1
Reviewers’ point of view • Significance • Approach • Innovation • Investigators • Environment
Anatomy of NIH grant application • Cover letter • Study section, funding institute, science area • Research plan • Specific aims, Background, Preliminary data, Research design • Additional materials • Work on revision
How have I done it? • Commit myself to hard work • Idea, preliminary studies, grant writing • Fight with English • A stupid farmer moves a mountain • Focus on science; writing adds clarity • Keep work on my idea until success • No pause after submission, more data for revision
An example: early sepsis diagnosis • Idea • septic macrophage can be detected by MRI with nanoparticles before organ failure • Seek grant got poor review • mice and patient exploration, fishing… • biological pathway? • What to do • approach is valid and valuable • no money? work >> 40 hrs/wk (<168 hrs/wk)