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Innovations in Neurological Device Platform Technologies

Explore advancements in extrinsic neurally controlled systems for restoring sensory-motor control. Learn about signal extraction and insertion methods, including stroke and amputation applications, and the future potential of device platform technologies. Discover the integration of neurotechnology with functional neuromuscular stimulation and emerging control interfaces.

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Innovations in Neurological Device Platform Technologies

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  1. Peter Konrad, MD PhD Director, Functional Neurosurgery Vanderbilt University Platform Technologies for Medical Devices:Case of the Brain-Machine Interface

  2. Disclosures Consulting: Medtronic Neurological; FHC Inc. Fiduciary Position: CMO – Neurotargeting LLC Will not discuss off label use of approved FDA products

  3. Device Platform Technology ? Neurological Device Platform Technology

  4. Emergence of Extrinsic Neurally Controlled Systems • Goals: Restore Useful Sensory-Motor Control • Methods: • Extract Control Information • Insert Sensory Feedback • Information Processing Stroke Motor Signal Extraction SCI Sensory Signal Insertion ALS Amputation

  5. Cortically Based Interface

  6. Beta Band (20-30Hz) activity following Go Cue in primary motor cortex Hochberg et al. Nature 442: 164-171, 2006

  7. Subcortical Based Interface: Motor Signal Extraction

  8. Sub-Cortical Based Interface: Sensory Signal Insertion

  9. Sub-Cortical Based Interface: Sensory Signal Insertion

  10. BMI Output: Where Should It Go?

  11. BMI Output: Where Should It Go?

  12. Functional Neuromuscular Stimulation:Output Interface Already Put in Practice Examine alternative user command interfaces -- based on facial and neck EMG signals, as well as head orientation. Courtesy: Dr. Hunter Peckham

  13. Intramuscular electrode Functional Neuromuscular Stimulation:Output Interface Already Put in Practice EMG based Control – hand grasp opening: brachioradialis | closing: trapezius EMG Courtesy: Dr. Hunter Peckham

  14. Future of Device Platform Technologies

  15. Future of Device Platform Technologies • Approved: signal insertion (+ a few signal extraction) implants • ? Signal processing needs • ? Body LAN • Can we take cues from computer / communications industry? Stroke Motor Signal Extraction SCI Sensory Signal Insertion ALS Amputation

  16. Device Platform Technology Neurological Device Platform Technology

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