Differentiating among incretin agents for type 2 diabetes weighing the evidence
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Differentiating Among Incretin Agents for Type 2 Diabetes: Weighing the Evidence - PowerPoint PPT Presentation

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Differentiating Among Incretin Agents for Type 2 Diabetes: Weighing the Evidence. Program Goals. Insulin Deficiency and Glucagon Hypersecretion in T2D. Postprandial Glucagon Is Excessive and Not Corrected by Exogenous Insulin. Incretin Hormome Physiology. Signal Transduction and GLP-1.

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Presentation Transcript

Program goals
Program Goals Weighing the Evidence

Incretin hormome physiology
Incretin Hormome Physiology Exogenous Insulin

Liraglutide exenatide black box warning risk of thyroid c cell tumors
Liraglutide/Exenatide: Black Box Warning TimeRisk of Thyroid C-Cell Tumors

Incretin based therapies concern about acute pancreatitis
Incretin-based Therapies: TimeConcern About Acute Pancreatitis

Sitagliptin and exenatide associated with increased risk for hospitalization for acute pancreatitis
Sitagliptin and Exenatide Associated With Increased Risk for Hospitalization for Acute Pancreatitis

Incretin based therapies renal impairment
Incretin-based Therapies: Renal Impairment Hospitalization for Acute Pancreatitis

Closing comments
Closing Comments Alpha-Cell Hyperplasia

Abbreviations Alpha-Cell Hyperplasia

Abbreviations cont
Abbreviations (cont) Alpha-Cell Hyperplasia

Abbreviations cont1
Abbreviations (cont) Alpha-Cell Hyperplasia

References Alpha-Cell Hyperplasia

References cont
References (cont) Alpha-Cell Hyperplasia

References cont1
References (cont) Alpha-Cell Hyperplasia

References cont2
References (cont) Alpha-Cell Hyperplasia

References cont3
References (cont) Alpha-Cell Hyperplasia

References cont4
References (cont) Alpha-Cell Hyperplasia